Evidence map›Paper›PMID 30289887›Full record

ArticlePloS one2018

The effect of modified locking methods and suture materials on Zone II flexor tendon repair-An ex vivo study.

Susumu Yoneda, Hirotaka Okubo, Stephen W Linderman, Nozomu Kusano, Matthew J Silva, Stavros Thomopoulos, Fuminori Kanaya, Richard H Gelberman

Open access · goldAbstract readComparative Study
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Cell-based tissue engineered flexor tendon allograft: A canine in vivo study.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024
    Article
  2. Article
  3. Article
  4. Stem cell-derived extracellular vesicles attenuate the early inflammatory response after tendon injury and repair.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Susumu YonedaDepartment of Orthopaedic Surgery, Washington University, St. Louis, Missouri, United States of America.ORCID 0000-0001-9466-2571
Hirotaka OkuboDepartment of Orthopedic Surgery, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Stephen W LindermanDepartment of Orthopaedic Surgery, Washington University, St. Louis, Missouri, United States of America.ORCID 0000-0002-1797-5870
Nozomu KusanoDepartment of Orthopedic Surgery, Tominaga-Kusano Hospital, Niigata, Japan.
Matthew J SilvaDepartment of Orthopaedic Surgery, Washington University, St. Louis, Missouri, United States of America.
Stavros ThomopoulosDepartment of Orthopedic Surgery, Columbia University, New York, New York, United States of America.
Fuminori KanayaDepartment of Orthopedic Surgery, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Richard H GelbermanDepartment of Orthopaedic Surgery, Washington University, St. Louis, Missouri, United States of America.
Washington University in St. Louis · USUniversity of the Ryukyus · JPColumbia University · USIto Hospital · JP

Funding

Enhanced Tendon Healing Through Growth Factor and Cell TherapiesR01AR062947 · NIAMS · WASHINGTON UNIVERSITY · PI GELBERMAN, RICHARD H, THOMOPOULOS, STAVROS · 2012 to 2022
$5.5M
Skeletal Disorders Training ProgramT32AR060719 · NIAMS · WASHINGTON UNIVERSITY · PI Roberto Civitelli · 2011 to 2026
$4.6M
NIAMS NIH HHS R01 AR062947NIAMS NIH HHS T32 AR060719
6 · The paper itself

Abstract

The failure rate of intrasynovial tendon repair is high due to substantial elongation at the repair site and to the development of adhesions between the tendon's surface and the surrounding digital sheath. To minimize these complications, we sought to reduce the incidence of gapping and to facilitate the initiation of early motion by improving the time zero structural properties of repair. The Winters-Gelberman 8-strand repair technique was modified by adding surface lock loops and by using Fiberwire suture material. Forty-eight canine flexor digitorum profundus tendons were transected and repaired with one of three 8-strand techniques (Pennington modified Kessler, half hitch loops, or surface locking Kessler) using either 3-0 Supramid or 4-0 Fiberwire suture. Biomechanical testing was performed to determine the physiologic and failure mode properties of the repairs. The surface locking Kessler technique improved repair maximum load, load necessary to create a 2 mm repair site gap, and yield force compared to the modified Kessler and half hitch loop techniques. Fiberwire suture improved maximum load, the load necessary to create a 2 mm repair site gap, stiffness, and yield force compared to Supramid suture. Failure occurred by both suture pull out and by suture breakage in the modified Kessler, Supramid suture repair group. Failure occurred consistently by suture breakage in the surface locking Kessler, Supramid suture repair group. These results reveal that a novel locking Kessler repair is significantly stronger than the current state-of-the art flexor tendon suture repair technique. The use of a surface locking Kessler technique with Fiberwire suture markedly improves the mechanical properties of intrasynovial tendon repair by reducing the risk of post-operative gapping and rupture.

Indexed as

SuturesSuture TechniquesAnimalsBiomechanical PhenomenaDogsElasticityEquipment FailureFemaleHindlimbNylonsPostoperative ComplicationsTendon InjuriesTendonsNylons

Identifiers

PMID30289887
PMCPMC6173425
OpenAlexW2894802398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.