Evidence map›Paper›PMID 30289806›Full record

ArticleAIDS (London, England)2019

Are European HIV cohort data within EuroCoord representative of the diagnosed HIV population?

Georgia Vourli, Anastasia Pharris, Francoise Cazein, Dominique Costagliola, Francois Dabis, Julia Del Amo, Valerie Delpech, Asuncion Díaz, Enrico Girardi, Annabelle Gourlay and 10 more

Abstract read
In one paragraph

Article in AIDS (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Human Immunodeficiency Virus Continuum of Care in 11 European Union Countries at the End of 2016 Overall and by Key Population: Have We Made Progress?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Georgia VourliDepartment of Hygiene, Epidemiology and Medical Statistics, Medical School, NKUA, Athens, Greece.
Anastasia PharrisEuropean Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Francoise CazeinSanté Publique France, The French National Public Health Agency.
Dominique CostagliolaSorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (IPLESP), Paris.
Francois DabisUniversité Bordeaux, ISPED, Centre INSERM U1219 - Bordeaux Population Health, Bordeaux, France.
Julia Del AmoNational Center of Epidemiology, Instituto de Salud Carlos III, Madrid, Spain.
Valerie DelpechPublic Health England, London, UK.
Asuncion DíazNational Center of Epidemiology, Instituto de Salud Carlos III, Madrid, Spain.
Enrico GirardiClinical Epidemiology Unit, National Institute for Infectious Diseases L. Spallanzani, Rome, Italy.
Annabelle GourlayInstitute for Global Health, University College London.
Barbara Gunsenheimer-BartmeyerSTI Unit, Department of Infectious Disease Epidemiology HIV/AIDS, Robert Koch-Institute, Berlin, Germany.
Victoria HernandoNational Center of Epidemiology, Instituto de Salud Carlos III, Madrid, Spain.
Georgios NikolopoulosMedical School, University of Cyprus, Nicosia, Cyprus.
Kholoud PorterInstitute for Global Health, University College London.
Magdalena RosińskaDepartment of Epidemiology of Infectious Diseases and Surveillance, National Institute of Public Health-National Institute of Hygiene, Warsaw, Poland.
Caroline SabinInstitute for Global Health, University College London.
Barbara SuligoiCentro Operativo AIDS, Istituto Superiore di Sanità, Rome, Italy.
Virginie SupervieSorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (IPLESP), Paris.
Ferdinand WitStichting HIV Monitoring, Amsterdam, The Netherlands.
Giota TouloumiDepartment of Hygiene, Epidemiology and Medical Statistics, Medical School, NKUA, Athens, Greece.

Funding

Medical Research Council MC_U122886351Medical Research Council MC_UU_12023/15Medical Research Council MR/M004236/1Medical Research Council [UK] G0000199Medical Research Council [UK] G0600337Medical Research Council [UK] G0900274Medical Research Council [UK] M004236
6 · The paper itself

Abstract

objectiveHIV cohorts are an important source of clinical data for informing public health policies and programmes. However, the generalizability of cohort findings to the wider population of people diagnosed with HIV in each country remains unclear. In this work, we assessed the representativeness of six large national HIV cohorts within Europe. DESIGN AND

methodsIndividual-level cohort data were provided from national cohorts in France, Germany, Greece, Italy, Spain and the United Kingdom. Analysis focused on new HIV diagnoses reported to The European Surveillance System (TESSy) during three time periods (2000-2004, 2005-2009 and 2010-2013), to allow for temporal changes. Cohort and TESSy records were matched and compared by age, sex, transmission mode, region of origin and CD4+ cell count at diagnosis. The probability of being included in each cohort given demographic characteristics was estimated and used to generate weights inversely proportional to the probability of being included.

resultsParticipating cohorts were generally representative of the national HIV-diagnosed population submitted to TESSy. However, people who inject drugs, those born in a country other than that reporting the data, those with low CD4 cell counts at diagnosis, and those more than 55 years were generally underrepresented in the cohorts examined.

conclusionThese European cohorts capture a representative sample of the HIV-diagnosed populations in each country; however some groups may be underrepresented.

Indexed as

Epidemiological MonitoringAdolescentAdultAgedCohort StudiesEuropeFemaleHIV InfectionsHumansMaleMiddle AgedSampling StudiesYoung Adult

Identifiers

PMID30289806
PMCPMC6415981

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.