Evidence map›Paper›PMID 30289549›Full record

ArticleNucleic acids research2019

CellMarker: a manually curated resource of cell markers in human and mouse.

Xinxin Zhang, Yujia Lan, Jinyuan Xu, Fei Quan, Erjie Zhao, Chunyu Deng, Tao Luo, Liwen Xu, Gaoming Liao, Min Yan and 7 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 946 papers.

0numbers the graph read from it
0cells of the map it votes in
946citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

946 citing papers in PubMed.

  1. Article
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  5. celltypeEnrich: a consensus-based scRNA-seq cluster annotation tool.bioRxiv : the preprint server for biology · 2026
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  15. mNature metabolism · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Immune niche composed of C1QNature communications · 2026
    Article
  20. Article

886 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Xinxin ZhangCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150081, China.
Yujia LanCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150081, China.
Jinyuan XuCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150081, China.
Fei QuanCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150081, China.
Erjie ZhaoCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150081, China.
Chunyu DengCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150081, China.
Tao LuoCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150081, China.
Liwen XuCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150081, China.
Gaoming LiaoCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150081, China.
Min YanCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150081, China.
Yanyan PingCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150081, China.
Feng LiCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150081, China.
Aiai ShiCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150081, China.
Jing BaiCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150081, China.
Tingting ZhaoDepartment of Neurology, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China.
Xia LiCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150081, China.
Yun XiaoCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150081, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the most fundamental questions in biology is what types of cells form different tissues and organs in a functionally coordinated fashion. Larger-scale single-cell sequencing and biology experiment studies are now rapidly opening up new ways to track this question by revealing substantial cell markers for distinguishing different cell types in tissues. Here, we developed the CellMarker database (http://biocc.hrbmu.edu.cn/CellMarker/ or http://bio-bigdata.hrbmu.edu.cn/CellMarker/), aiming to provide a comprehensive and accurate resource of cell markers for various cell types in tissues of human and mouse. By manually curating over 100 000 published papers, 4124 entries including the cell marker information, tissue type, cell type, cancer information and source, were recorded. At last, 13 605 cell markers of 467 cell types in 158 human tissues/sub-tissues and 9148 cell makers of 389 cell types in 81 mouse tissues/sub-tissues were collected and deposited in CellMarker. CellMarker provides a user-friendly interface for browsing, searching and downloading markers of diverse cell types of different tissues. Furthermore, a summarized marker prevalence in each cell type is graphically and intuitively presented through a vivid statistical graph. We believe that CellMarker is a comprehensive and valuable resource for cell researches in precisely identifying and characterizing cells, especially at the single-cell level.

Indexed as

Databases, GeneticSoftwareAnimalsHumansMiceSequence AnalysisSingle-Cell Analysis

Identifiers

PMID30289549
PMCPMC6323899

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.