Evidence map›Paper›PMID 30289426›Full record

Trial reportAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2019

The Association of Changes in Pain Acceptance and Headache-Related Disability.

Jason Lillis, J Graham Thomas, Richard B Lipton, Lucille Rathier, Julie Roth, Jelena Pavlovic, Kevin C O'Leary, Dale S Bond

Registry-linked trialOpen access · bronzeAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01197196 (Behavioral Weight Loss as a Treatment for Migraine in Obese Women), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01197196 nacompletednot on this map

Behavioral Weight Loss as a Treatment for Migraine in Obese Women

TypeinterventionalSponsorThe Miriam HospitalRan2012 to 2017Enrolled112ConditionsMigraine, ObesityArmsBehavioral Weight Loss Intervention, Migraine Education
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Review
  3. The Role of Pain Inflexibility and Acceptance among Headache and Temporomandibular Disorders Patients.International journal of environmental research and public health · 2022
    Article
  4. Review
  5. Fear, Avoidance, and Disability in Headache Disorders.Current pain and headache reports · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jason LillisDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA.
J Graham ThomasDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA.
Richard B LiptonDepartment of Neurology and the Montefiore Headache Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Lucille RathierDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA.
Julie RothDepartment of Neurology, Alpert Medical School of Brown University, Providence, RI, USA.
Jelena PavlovicDepartment of Neurology and the Montefiore Headache Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Kevin C O'LearyDepartment of Psychiatry and Human Behavior, The Miriam Hospital Weight Control and Diabetes Research Center, Providence, RI, USA.
Dale S BondDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA.
Providence College · USAlbert Einstein College of Medicine · US

Funding

Behavioral Weight Loss as a Treatment for Migraine in Obese WomenR01NS077925 · NINDS · MIRIAM HOSPITAL · PI BOND, DALE S · 2012 to 2015
$2.1M
The relation of migraine to daily hormone patterns and menopausal stageK23AG049466 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI PAVLOVIC, JELENA · 2016 to 2021
$918k
Using Novel Behavioral Approaches to Improve Long-Term Weight Loss OutcomesK23DK097143 · NIDDK · MIRIAM HOSPITAL · PI LILLIS, JASON · 2013 to 2017
$863k
NIA NIH HHS K23 AG049466NIDDK NIH HHS K23 DK097143NINDS NIH HHS R01 NS077925
6 · The paper itself

Abstract

backgroundMigraine accounts for substantial suffering and disability. Previous studies show cross-sectional associations between higher pain acceptance and lower headache-related disability in individuals with migraine, but none has evaluated this association longitudinally during migraine treatment. PURPOSE: This study evaluated whether changes in pain acceptance were associated with changes in headache-related disability and migraine characteristics in a randomized controlled trial (Women's Health and Migraine) that compared effects of behavioral weight loss (BWL) treatment and migraine education (ME) on headache frequency in women with migraine and overweight/obesity.

methodsThis was a post hoc analysis of 110 adult women with comorbid migraine and overweight/obesity who received 16 weeks of either BWL or ME. Linear and nonlinear mixed effects modeling methods were used to test for between-group differences in change in pain acceptance, and also to examine the association between change in pain acceptance and change in headache disability.

resultsBWL and ME did not differ on improvement in pain acceptance from baseline across post-treatment and follow-up. Improvement in pain acceptance was associated with reduced headache disability, even when controlling for intervention-related improvements in migraine frequency, headache duration, and pain intensity.

conclusionsThis study is the first to show that improvements in pain acceptance following two different treatments are associated with greater reductions in headache-related disability, suggesting a potential new target for intervention development. CLINICAL TRIALS INFORMATION: NCT01197196.

Indexed as

Outcome Assessment, Health CarePatient Education as TopicWeight LossWeight Reduction ProgramsAdolescentAdultComorbidityFemaleHumansLongitudinal StudiesMiddle AgedMigraine DisordersObesityOverweightPersons with DisabilitiesSeverity of Illness IndexAcceptanceDisabilityHeadacheMigraineObesityPain

Identifiers

PMID30289426
PMCPMC6546934
OpenAlexW2894794311

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.