ArticleThe New phytologist2019
Albugo candida race diversity, ploidy and host-associated microbes revealed using DNA sequence capture on diseased plants in the field.
Article in The New phytologist, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 57 citations in OpenAlex.
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- Methods, applications, and computational challenges in bait capture enrichment.Cell reports methods · 2025Review
- Population Genomics Reveals Distinct Lineage of the Asian Soybean Rust Fungus Phakopsora pachyrhizi in the United States of America Unrelated to Brazilian Populations.Molecular plant pathology · 2025Article
- Developing a crop- wild-reservoir pathogen system to understand pathogen evolution and emergence.eLife · 2025Article
- Infection Patterns ofPlants (Basel, Switzerland) · 2025Article
- Tools for pathogen genetic surveillance: Lessons from the ash dieback invasion of Europe.PLoS pathogens · 2024Review
- The Arabidopsis WRR4A and WRR4B paralogous NLR proteins both confer recognition of multiple Albugo candida effectors.The New phytologist · 2023Article
- How do emerging long-read sequencing technologies function in transforming the plant pathology research landscape?Plant molecular biology · 2022Review
- Multiomics Reveals the Effect of Root Rot on Polygonati Rhizome and Identifies Pathogens and Biocontrol Strain.Microbiology spectrum · 2022Article
- Mitigating the threat of emerging infectious diseases; a coevolutionary perspective.Virulence · 2021Article
- Fantastic Downy Mildew Pathogens and How to Find Them: Advances in Detection and Diagnostics.Plants (Basel, Switzerland) · 2021Review
- Current Status of the Disease-Resistant Gene(s)/QTLs, and Strategies for Improvement inFrontiers in plant science · 2021Review
- Identification of Avramr1 from Phytophthora infestans using long read and cDNA pathogen-enrichment sequencing (PenSeq).Molecular plant pathology · 2020Article
- High-resolution expression profiling of selected gene sets during plant immune activation.Plant biotechnology journal · 2020Article
- Genomic and Molecular Perspectives of Host-pathogen Interaction and Resistance Strategies against White Rust in Oilseed Mustard.Current genomics · 2020Review
- Evolutionary genomics of anthroponosis in Cryptosporidium.Nature microbiology · 2019Article
- Transgressive segregation reveals mechanisms ofProceedings of the National Academy of Sciences of the United States of America · 2019Article
- Pathogen enrichment sequencing (PenSeq) enables population genomic studies in oomycetes.The New phytologist · 2019Article
- Oomycetes Used in Arabidopsis Research.The arabidopsis book · 2019Article
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12 authors at 7 institutions in 2 countries.
Funding
Abstract
Physiological races of the oomycete Albugo candida are biotrophic pathogens of diverse plant species, primarily the Brassicaceae, and cause infections that suppress host immunity to other pathogens. However, A. candida race diversity and the consequences of host immunosuppression are poorly understood in the field. We report a method that enables sequencing of DNA of plant pathogens and plant-associated microbes directly from field samples (Pathogen Enrichment Sequencing: PenSeq). We apply this method to explore race diversity in A. candida and to detect A. candida-associated microbes in the field (91 A. candida-infected plants). We show with unprecedented resolution that each host plant species supports colonization by one of 17 distinct phylogenetic lineages, each with an unique repertoire of effector candidate alleles. These data reveal the crucial role of sexual and asexual reproduction, polyploidy and host domestication in A. candida specialization on distinct plant species. Our bait design also enabled phylogenetic assignment of DNA sequences from bacteria and fungi from plants in the field. This paper shows that targeted sequencing has a great potential for the study of pathogen populations while they are colonizing their hosts. This method could be applied to other microbes, especially to those that cannot be cultured.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.