ArticlePituitary2018
Work disability and its determinants in patients with pituitary tumor-related disease.
Article in Pituitary, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review and network meta-analysis assess the comparative efficacy and safety of transsphenoidal surgery for pituitary tumor.Neurosurgical review · 2021Pooled it
- Low work ability and high disability burden in Cushing's syndrome: a multicenter cohort study.Journal of endocrinological investigation · 2026Observational
- Quality of life questionnaires in patients with acromegaly: a scoping review.Journal of patient-reported outcomes · 2026Article
- Return to work and factors influencing recovery after endoscopic transsphenoidal surgery for hypothalamic and pituitary tumors.Scientific reports · 2025Article
- Urinary oxytocin secretion after pituitary surgery, early arginine vasopressin deficiency and syndrome of inappropriate antidiuresis.Endocrine · 2025Article
- Coping strategies in patients undergoing surgery treatment for pituitary tumour in China: A cross-sectional survey.Nursing open · 2023Article
- Article
- The impact of vestibular schwannoma and its management on employment.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Article
- Angpt2/Tie2 autostimulatory loop controls tumorigenesis.EMBO molecular medicine · 2022Article
- First-line surgery in prolactinomas: lessons from a long-term follow-up study in a tertiary referral center.Journal of endocrinological investigation · 2021Article
- Article
- Healthcare utilization and costs among prolactinoma patients: a cross-sectional study and analysis of determinants.Pituitary · 2021Article
- Extended Support Within a Person-Centered Practice After Surgery for Patients With Pituitary Tumors: Protocol for a Quasiexperimental Study.JMIR research protocols · 2020Article
- Machine learning applications in imaging analysis for patients with pituitary tumors: a review of the current literature and future directions.Pituitary · 2020Review
- Unmet needs and recommendations to improve meningioma care through patient, partner, and health care provider input: a mixed-method study.Neuro-oncology practice · 2020Article
- Healthcare utilization and costs among patients with non-functioning pituitary adenomas.Endocrine · 2019Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
introductionPituitary tumors may have a considerable impact on patients' functional status, including paid employment, yet research in this area is sparse.
objectiveTo describe work disability and its determinants in patients treated for a pituitary tumor.
methodsCross-sectional study including patients treated for a pituitary tumor in the working age (18-65 years), who completed five validated questionnaires assessing work disability [Short Form-Health and Labour Questionnaire, Work Role Functioning Questionnaire 2.0 (WRFQ)], health-related quality of life (HRQoL) and utility (Short Form-36, EuroQoL) and disease burden (Leiden Bother and Needs Questionnaire-Pituitary). Additional data were extracted from the medical records (age, gender, tumor type, treatment, date of diagnosis) and self-reports (marital status, education, endocrine status). Associations of disease-specific and sociodemographic characteristics, HRQoL, and disease burden with (not) having a paid job were examined through multivariate logistic regression.
resultsWe included 241 patients (61% female, median age 53 years, median time since diagnosis 11 years), of whom 68 (28%) were without a paid job. Patients who had acromegaly, Cushing's disease, (pan)hypopituitarism, radiotherapy, were single, less educated, lower HRQoL, and increased disease burden were more often without a paid job (p < 0.05). Among those with paid jobs, 41% reported health-related absenteeism in the previous year. The three work incapacitating problems reported by the largest proportion of patients were within the mental and social domain (WRFQ).
conclusionWork disability among patients treated for a pituitary tumor is substantial. As impact on social functioning is high, it is strongly advised to incorporate work disability during clinical guidance of patients.
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