Evidence map›Paper›PMID 30288356›Full record

ArticleOncoimmunology

Charlotte M Mousset, Willemijn Hobo, Yun Ji, Hanny Fredrix, Valeria De Giorgi, Robert D Allison, Michel G D Kester, J H Frederik Falkenburg, Nicolaas P M Schaap, Joop H Jansen and 3 more

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Review
  3. Novel strategies to manage CAR-T cell toxicity.Nature reviews. Drug discovery · 2025
    Review
  4. Presetting CAR-T cells during ex vivo biomanufacturing.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  5. Review
  6. Review
  7. Article
  8. Stem-like CD8Frontiers in immunology · 2024
    Review
  9. Article
  10. Article
  11. Challenges and new technologies in adoptive cell therapy.Journal of hematology & oncology · 2023
    Review
  12. Review
  13. Review
  14. The magic of small-molecule drugs duringFrontiers in immunology · 2023
    Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Charlotte M MoussetDepartment of Laboratory Medicine - Laboratory of Hematology; Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Willemijn HoboDepartment of Laboratory Medicine - Laboratory of Hematology; Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0002-8206-8185
Yun JiExperimental Transplantation and Immunology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-6340-7009
Hanny FredrixDepartment of Laboratory Medicine - Laboratory of Hematology; Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Valeria De GiorgiInfectious Diseases Section, Department of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-5296-8628
Robert D AllisonInfectious Diseases Section, Department of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-8458-5250
Michel G D KesterDepartment of Hematology - Laboratory of Experimental Hematology, Leiden University Medical Center, Leiden, The Netherlands.
J H Frederik FalkenburgDepartment of Hematology - Laboratory of Experimental Hematology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-9819-4813
Nicolaas P M SchaapDepartment of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0001-7696-4752
Joop H JansenDepartment of Laboratory Medicine - Laboratory of Hematology; Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0001-9459-568X
Luca GattinoniExperimental Transplantation and Immunology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-2239-3282
Harry DolstraDepartment of Laboratory Medicine - Laboratory of Hematology; Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0002-3998-687X
Anniek B van der WaartDepartment of Laboratory Medicine - Laboratory of Hematology; Radboud Institute of Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0001-5986-3060
Radboud University Nijmegen · NLNational Institutes of Health · USLeiden University Medical Center · NL

Funding

Programming T Cell Fates for Therapeutic UseZIABC011480 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI GATTINONI, LUCA · 2013 to 2019
$7.4M
6 · The paper itself

Abstract

Adoptive T cell therapy has shown clinical potential for patients with cancer, though effective treatment is dependent on longevity and potency of the exploited tumor-reactive T cells. Previously, we showed that

Indexed as

adoptive transferAKTCD8+ T cellglycolysispolyfunctionalitystem cell memory

Identifiers

PMID30288356
PMCPMC6169586
OpenAlexW2886950014

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.