Evidence map›Paper›PMID 30288330›Full record

ArticleHepatology, medicine and policy2018

Hepatitis C virus prevention and care for drug injectors: the French approach.

Jean-Michel Delile, Victor de Ledinghen, Marie Jauffret-Roustide, Perrine Roux, Brigitte Reiller, Juliette Foucher, Daniel Dhumeaux

Open access · hybridAbstract read
In one paragraph

Article in Hepatology, medicine and policy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Sex Disparities in Hepatitis C Treatment Initiation: Role of Universal Access to DAA in France (ANRS FANTASIO 2).Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  3. Review
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  15. The Elimination of Hepatitis C as a Public Health Threat.Cold Spring Harbor perspectives in medicine · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Jean-Michel DelileComité d'étude et d'information sur la drogue et les addictions (CEID), 20, place Pey-Berland, 33000 Bordeaux, France.ORCID 0000-0002-9073-2568
Victor de Ledinghen2Hôpital du Haut-Lévêque, Pessac, France.
Marie Jauffret-Roustide3Cermes 3 (Inserm U988/CNRS UMR 8211/EHESS/Paris Descartes University) and French National Public Health Agency, Paris, France.
Perrine Roux4Inserm UMR1252/IRD/SESSTIM/Aix-Marseille University/ORS PACA, Marseille, France.
Brigitte ReillerComité d'étude et d'information sur la drogue et les addictions (CEID), 20, place Pey-Berland, 33000 Bordeaux, France.
Juliette Foucher2Hôpital du Haut-Lévêque, Pessac, France.
Daniel Dhumeaux5Université de Paris-Est, Créteil, France.
Hôpital Cardiologique du Haut-Lévêque · FRNutrition Metabolism Aquaculture · FRDélégation Paris 5 · FRInserm · FRUniversité Paris-Est Créteil · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After France removed hepatitis C treatment reimbursement restrictions on 25 May 2016, an expert report presented recommendations, which focused on vulnerable groups including people who inject drugs (PWID). This commentary presents the key points of the chapter with a particular focus on policy. Thanks to the official lifting of restrictions based on disease stage and to the excellent efficacy and tolerance of the new DAA (Direct-Acting Antivirals) among PWID, the main issue is to improve the HCV care cascade. In France, many HCV-infected PWID, especially active/current PWID, remain undiagnosed and unlinked to care. Our challenge is to improve HCV screening by point of care testing (POCT), outreach methods with mobile teams, rapid tests, FibroScan, etc. and to provide PWID with appropriate services in all the settings they attend, such as drug treatment or harm reduction services, social services, prisons, etc. Another important issue is the prevention of reinfection through comprehensive and long-term follow-up. The report recommends a new national policy: testing and treating PWID as a priority, since this is the best way to eliminate HCV infection. It requires a global strategy consisting of combined and long-term interventions: prevention, outreach, screening, DAA, drug treatment programs including opiate substitution treatment (OST) and various harm reduction programs, including needle exchange programs (NEP). Ideally, these services should be delivered in the same place with an integrated approach. This should lead to meeting the national objective set by the government of eliminating hepatitis C by 2025.

Indexed as

Drug usersFranceGuidelinesHarm reductionHCVInjectionPWIDStrategyTreatment costs

Identifiers

PMID30288330
PMCPMC5987624
OpenAlexW2807534861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.