Evidence map›Paper›PMID 30288287›Full record

ArticleUnited European gastroenterology journal2018

Post-infectious IBS: Defining its clinical features and prognosis using an internet-based survey.

Tim Card, Paul Enck, Giovanni Barbara, Guy Ee Boeckxstaens, Javier Santos, Fernando Azpiroz, Fermin Mearin, Qasim Aziz, John Marshall, Robin Spiller

Open access · greenAbstract read
In one paragraph

Article in United European gastroenterology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 61 citations in OpenAlex.

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  10. 5-HTLaboratory investigation; a journal of technical methods and pathology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 5 countries.

Tim CardNottingham Digestive Diseases Centre, University of Nottingham and National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK.
Paul EnckDepartment of Internal Medicine VI: Psychosomatic Medicine and Psychotherapy, University Hospital Tuebingen, Tuebingen, Germany.
Giovanni BarbaraDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
Guy Ee BoeckxstaensTranslational Research Center for Gastrointestinal Disorders, University Hospital Leuven, Leuven, Belgium.
Javier SantosDigestive System Research Unit, University Hospital Vall d'Hebron, Bellaterra, Spain.
Fernando AzpirozDigestive System Research Unit, University Hospital Vall d'Hebron, Bellaterra, Spain.
Fermin MearinInstitute of Functional and Motor Disorders, Centro Médico Teknon, Barcelona, Spain.
Qasim AzizWingate Institute of Neurogastroenterology, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
John MarshallDepartment of Medicine, McMaster University, Ontario, Canada.
Robin SpillerNottingham Digestive Diseases Centre, University of Nottingham and National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK.ORCID https://orcid.org/0000-0001-6371-4500
Nottingham University Hospitals NHS Trust · GBHospital Quirón Teknon · ESKU Leuven · BEMcMaster University · CAQueen Mary University of London · GBUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastrointestinal infection is an important risk factor for developing irritable bowel syndrome (IBS). Our aim was to characterise post-infectious IBS (PI-IBS) compared to other IBS patients.

methodsAn internet survey of IBS patients using Rome III diagnostic questionnaire, Hospital Anxiety and Depression Scale (HADS) and Patient Health Questionnaire-12 Somatic Symptom (PHQ12-SS) scale score documenting the mode of onset was conducted.

resultsA total of 7811 participants (63.2% female), of whom 1004 (13.3%) met criteria for PI-IBS, were studied. Seventy per cent of PI-IBS patients described sudden onset, 35% onset while travelling, 49.6% vomiting, 49.9% fever and 20.3% bloody diarrhoea. Compared to other IBS individuals, PI-IBS was significantly associated with living in Northern Europe and North America, having a hysterectomy, not having an appendicectomy, higher PHQ12-SS score and having more than one toilet in the family home. PI-IBS patients had more frequent stools. At one year recovery rate in the PI-IBS and non-PI-IBS group was 19.7% and 22.2%,

conclusionPI-IBS accounts for around 13% of all IBS in this internet sample, with some distinctive features but a similar prognosis to the remainder.

Indexed as

infectioninternetIrritableprospectivesurvey

Identifiers

PMID30288287
PMCPMC6169057
OpenAlexW2800399579

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.