Evidence map›Paper›PMID 30288277›Full record

ArticleUnited European gastroenterology journal2018

Nitrous oxide cryotherapy ablation for refractory gastric antral vascular ectasia.

Anish A Patel, Arvind J Trindade, David L Diehl, Harshit S Khara, Tai-Ping Lee, Calvin Lee, Amrita Sethi

Registry-linked trialAbstract read
In one paragraph

Article in United European gastroenterology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04760873 (Gastric Antral Vascular Ectasia Treatment With Balloon Cryotherapy), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04760873 nawithdrawnnot on this mapstarted 2020, after this paper: background citation

Gastric Antral Vascular Ectasia Treatment With Balloon Cryotherapy: A Multicenter Prospective Trial

TypeinterventionalSponsorH. Lee Moffitt Cancer Center and Research InstituteRan2020 to 2024Enrolled0ConditionsGAVE - Gastric Antral Vascular Ectasia, Bleeding, Bleeding GastricArmscryotherapy
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Freezing our way to a cure?iGIE : innovation, investigation and insights · 2024
    Review
  2. Review
  3. Review
  4. Potential role of new technological innovations in nonvariceal hemorrhage.World journal of gastrointestinal endoscopy · 2019
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Anish A PatelColumbia University Medical Center, Division of Digestive and Liver Disease, New York, NY, USA.
Arvind J TrindadeZucker School of Medicine at Hofstra/Northwell, Northwell Health System, Division of Gastroenterology, Long Island Jewish Medical Center, New Hyde Park, NY, USA.ORCID https://orcid.org/0000-0002-4132-0014
David L DiehlDepartment of Gastroenterology, Geisinger Medical Center, Danville, PA, USA.
Harshit S KharaDepartment of Gastroenterology, Geisinger Medical Center, Danville, PA, USA.
Tai-Ping LeeZucker School of Medicine at Hofstra/Northwell, Northwell Health System, Division of Gastroenterology, Long Island Jewish Medical Center, New Hyde Park, NY, USA.
Calvin LeeZucker School of Medicine at Hofstra/Northwell, Northwell Health System, Division of Gastroenterology, Long Island Jewish Medical Center, New Hyde Park, NY, USA.
Amrita SethiColumbia University Medical Center, Division of Digestive and Liver Disease, New York, NY, USA.
Northwell Health · USColumbia University Irving Medical Center · USGeisinger Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArgon plasma coagulation (APC) is typically the first-line therapy for gastric antral vascular ectasia (GAVE). However, many patients are refractory to APC ablation.

objectiveWe examined the safety and efficacy of nitrous oxide CryoBalloon cryotherapy ablation for GAVE refractory to APC.

methodsThis is a retrospective review of patients with refractory GAVE treated with the CryoBalloon system. Technical success was defined as successful ablation of the visualized GAVE. Clinical success was defined by transfusion independence and percentage of GAVE that was eradicated.

resultsTwenty-three patients with GAVE were included, of whom 16 patients (70%) had two treatments with the CryoBalloon and seven patients (30%) had one treatment. Technical success was achieved in all patients. At six months, 19/23 (83%) were transfusion independent, while 20/23 (87%) had more than 75% of the GAVE eradicated. Patients were transfused an average of 1.8 units/month one year prior to cryotherapy and an average of 0.3 units/month up to six months post-cryotherapy (

conclusionsCryoBalloon ablation is an efficacious and safe modality for the treatment of GAVE. Prospective studies need to be conducted to determine comparative results to standard therapies.

Indexed as

Ablationcryotherapygastrointestinal bleedingwatermelon stomach

Identifiers

PMID30288277
PMCPMC6169040
OpenAlexW2808195771

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.