Evidence map›Paper›PMID 30288174›Full record

ReviewBiotechnology for biofuels2018

Lignin-carbohydrate complexes: properties, applications, analyses, and methods of extraction: a review.

Dmitry Tarasov, Mathew Leitch, Pedram Fatehi

Abstract readReview
In one paragraph

Review in Biotechnology for biofuels, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed.

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  20. Strategies Toward Synthesis and Conversion of Lignin Model Compounds.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Review

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dmitry Tarasov1Chemical Engineering Department, Lakehead University, 955 Oliver Road, Thunder Bay, ON P7B 5E1 Canada.
Mathew Leitch2Natural Resource Management Faculty, Lakehead University, 955 Oliver Road, Thunder Bay, ON P7B 5E1 Canada.
Pedram Fatehi1Chemical Engineering Department, Lakehead University, 955 Oliver Road, Thunder Bay, ON P7B 5E1 Canada.ORCID 0000-0002-3874-5089

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complexity of lignin and hemicellulose segmentation has been known since the middle of the ninetieth century. Studies confirmed that all lignin units in coniferous species and 47-66% of lignin moieties in deciduous species are bound to hemicelluloses or cellulose molecules in lignin-carbohydrate complexes (LCC). Different types and proportions of lignin and polysaccharides present in biomass lead to the formation of LCC with a great variety of compositions and structures. The nature and amount of LCC linkages and lignin substructures affect the efficiency of pulping, hydrolysis, and digestibility of biomass. This review paper discusses the structures, compositions, and properties of LCC present in biomass and in the products obtained via pretreating biomass. Methods for extracting, fractionating, and analyzing LCC of biomass, pulp, and spent pulping liquors are critically reviewed. The main perspectives and challenges associated with these technologies are extensively discussed. LCC could be extracted from biomass following varied methods, among which dimethyl sulfoxide or dioxane (Björkman's) and acetic acid (LCC-AcOH) processes are the most widely applied. The oxidation and methylation treatments of LCC materials elucidate the locations and frequency of binding sites of hemicelluloses to lignin. The two-dimensional nuclear magnetic resonance analysis allows the identification of the structure and the quantity of lignin-carbohydrate bonds involved in LCC. LCC application seems promising in medicine due to its high anti-HIV, anti-herpes, and anti-microbial activity. In addition, LCC was successfully employed as a precursor for the preparation of spherical biocarriers.

Indexed as

FractionationLignin–carbohydrate complex (LCC)Milled wood ligninNMRSustainable chemicals

Identifiers

PMID30288174
PMCPMC6162904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.