ArticleCancer management and research2018
Young age increases the risk of lymph node positivity in papillary thyroid cancer patients: a SEER data-based study.
Article in Cancer management and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Factors associated with occult lateral lymph node metastases in patients with clinically lymph node negative papillary thyroid carcinoma: a systematic review and meta-analysis.Frontiers in endocrinology · 2024Pooled it
- Clinical characteristics and risk analysis of lymph node metastasis in patients with cN0 differentiated thyroid carcinoma.Scientific reports · 2026Article
- Sonographic Assessment of Peripheral Lymph Nodes In Early-Stage Mycosis Fungoides: Diagnostic Value And Prognostic Implications.Dermatology practical & conceptual · 2026Article
- A nomogram for predicting the central lymph node metastasis in double primary carcinoma involving thyroid carcinoma.Gland surgery · 2025Article
- Development and validation of a machine learning model for central compartmental lymph node metastasis in solitary papillary thyroid microcarcinoma via ultrasound imaging features and clinical parameters.BMC medical imaging · 2025Article
- Distinct risk factors of lateral lymph node metastasis in patients with papillary thyroid cancer based on age stratification.BMC surgery · 2024Article
- BRAFCancers · 2023Article
- BRAF, TERT and HLA-G Status in the Papillary Thyroid Carcinoma: A Clinicopathological Association Study.International journal of molecular sciences · 2023Article
- Risk factors, prognostic predictors, and nomograms for pancreatic cancer patients with initially diagnosed synchronous liver metastasis.World journal of gastrointestinal oncology · 2023Article
- Occult Central Lymph Node Metastasis in cN0 Papillary Thyroid Carcinoma Patients Undergoing TOETVA Procedure.Journal of thyroid research · 2023Article
- Article
- Clinical assessment of T2 papillary thyroid carcinoma: a retrospective study conducted at a single tertiary institution.Scientific reports · 2022Article
- Risk Assessment of Liver Metastasis in Pancreatic Cancer Patients Using Multiple Models Based on Machine Learning: A Large Population-Based Study.Disease markers · 2022Article
- Central Compartment Lymph Nodes Have Distinct Metastatic Patterns in Different Age Groups.Frontiers in endocrinology · 2022Article
- Reevaluation of Criteria and Establishment of Models for Total Thyroidectomy in Differentiated Thyroid Cancer.Frontiers in oncology · 2021Article
- Clinical Relevance and Management of Recurrent Laryngeal Nerve Inlet Zone Lymph Nodes Metastasis in Papillary Thyroid Cancer.Frontiers in endocrinology · 2021Article
- A national database analysis for factors associated with thyroid cancer occurrence.Scientific reports · 2020Article
- Young age increases the risk of lymph-node metastasis in patients with muscle-invasive bladder urothelial carcinoma.BMC cancer · 2020Article
- Lymph node metastasis in young and middle-aged papillary thyroid carcinoma patients: a SEER-based cohort study.BMC cancer · 2020Article
- Risk factors of papillary thyroid microcarcinoma that predispose patients to local recurrence.PloS one · 2020Article
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10 authors.
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Abstract
introductionCurrently in papillary thyroid cancer (PTC), the correlation between lymph node positivity (LN+) and patient's age at diagnosis is still inconclusive. The aim of this study was to investigate whether younger PTC patients had higher LN+ rates. PATIENTS AND
methodsFrom the 1998-2013 Surveillance, Epidemiology, and End Results database, we analyzed PTC patients with at least 1 LN examined. The patients were divided into 5 groups by age separately for each T stage: ≤30; 31-40; 41-50; 51-60; >60 years.
resultsA total of 46,077 PTC patients were identified, including 8,386 (18.2%) patients aged ≤30 years, 10,971 (23.8%) patients aged 31-40 years, 11,646 (25.3%) patients aged 41-50 years, 8,596 (18.7%) patients aged 51-60 years, and 6,478 (14.1%) patients aged >60 years. In each T stage, LN+ rates were inversely associated with age at diagnosis, which was validated by multivariate logistic regression analysis (
conclusionWe identified that younger PTC patients have an increased predisposition for LN+ regardless of T stage. This finding could help surgeons to select the optimal treatment for younger PTC patients.
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