Evidence map›Paper›PMID 30288101›Full record

ArticleCancer management and research2018

Low expression of VSIG4 is associated with poor prognosis in hepatocellular carcinoma patients with hepatitis B infection.

Sicong Zhu, Wenliang Tan, Wenxin Li, Rui Zhou, Xiaolin Wu, Xianqing Chen, Wenda Li, Changzhen Shang, Yajin Chen

Open access · goldAbstract read
In one paragraph

Article in Cancer management and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sicong ZhuGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat- sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Wenliang TanGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat- sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Wenxin LiGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat- sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Rui ZhouGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat- sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Xiaolin WuGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat- sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Xianqing ChenGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat- sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Wenda LiDepartment of Hepatobiliary Surgery, Sun Yat- sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China, shangcz_sysu@163.com, cyj0509@126.com.
Changzhen ShangDepartment of Hepatobiliary Surgery, Sun Yat- sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China, shangcz_sysu@163.com, cyj0509@126.com.
Yajin ChenDepartment of Hepatobiliary Surgery, Sun Yat- sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China, shangcz_sysu@163.com, cyj0509@126.com.
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundV-set and immunoglobulin domain containing protein 4 (VSIG4) was reported to play an important role in tumorigenesis. However, the expression and clinical relevance in hepatocellular carcinoma (HCC) remain unknown. MATERIALS AND

methodsFirst, the mRNA profiles of HCC were screened from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus databases.

resultsBioinformatics analysis showed that

conclusionOur study suggests that VSIG4 is downregulated in HCC, and low expression of VSIG4 is associated with poor prognosis in hepatitis B virus-related HCC patients.

Indexed as

bioinformatics analysishepatitis B infectionhepatocellular carcinomaVSIG4

Identifiers

PMID30288101
PMCPMC6159793
OpenAlexW2891595121

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.