Evidence map›Paper›PMID 30288068›Full record

ArticleInfection and drug resistance2018

Phenotypic and genotypic drug sensitivity of

Biniam Wondale, Girmay Medhin, Gemeda Abebe, Samuel Tolosa, Temesgen Mohammed, Takele Teklu, Rembert Pieper, Gobena Ameni

Abstract read
In one paragraph

Article in Infection and drug resistance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Discordance between genotypic and phenotypic methods for the detection of rifampicin and isoniazid resistantJournal of clinical tuberculosis and other mycobacterial diseases · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Prevalence ofJournal of clinical tuberculosis and other mycobacterial diseases · 2023
    Article
  6. Article
  7. Tropical medicine and infectious disease · 2022
    Review
  8. Drug sensitivity of clinical isolates ofFrontiers in public health · 2022
    Article
  9. Spoligotyping of Clinical Isolates ofFrontiers in public health · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Drug Resistance Pattern ofInfection and drug resistance · 2021
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Biniam WondaleAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia, biniamw2005@yahoo.com.
Girmay MedhinAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia, biniamw2005@yahoo.com.
Gemeda AbebeMycobacteriology Research Center, Jimma University, Jimma, Ethiopia.
Samuel TolosaAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia, biniamw2005@yahoo.com.
Temesgen MohammedAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia, biniamw2005@yahoo.com.
Takele TekluAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia, biniamw2005@yahoo.com.
Rembert PieperJ. Craig Venter Institute, Rockville, MD, USA.
Gobena AmeniAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia, biniamw2005@yahoo.com.

Funding

Systems Biology for Molecular Analysis of Tuberculosis in EthiopiaU01HG007472 · NHGRI · ADDIS ABABA UNIVERSITY · PI AMENI, GOBENA · 2013 to 2016
$1.2M
NHGRI NIH HHS U01 HG007472
6 · The paper itself

Abstract

backgroundKnowledge of drug-sensitivity patterns of MATERIALS AND

methodsA total of 161 MTBC isolates (153 from new cases and eight re-treatment TB cases) were isolated using Lowenstein Jensen medium of which 126 isolates were able to be tested for drug sensitivity by BACTEC™MGIT™ 960 system, while all the 161 isolates were tested by GenoType

resultsOn the basis of MGIT 960 system, the prevalence of mono-resistance was 9.2% (11/119) in the new cases, although neither poly-resistance nor multidrug resistance (MDR) was recorded in these cases. On the basis of GenoType MTBDR

conclusionThe magnitude of drug resistance was relatively low in the new TB cases of South Omo as compared to the reports from the other regions of the country. This is encouraging and hence the TB Control Program in the Zone should strengthen its program so that the emergence of drug resistance is inhibited.

Indexed as

drug resistanceMGIT 960MTBDRplus

Identifiers

PMID30288068
PMCPMC6161742

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.