ArticleScientific reports2018
Molecular characterization, antimicrobial resistance and clinico-bioinformatics approaches to address the problem of extended-spectrum β-lactamase-producing Escherichia coli in western Saudi Arabia.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Emerging co-occurrence of mcr-10 and broad-spectrum β-lactamase genes in Enterobacterales from surface waters in Brazil.Environmental monitoring and assessment · 2026Article
- OXA-244-producing Escherichia coli isolated from a dog in Portugal.Veterinary research communications · 2025Article
- Clinical and epidemiological characteristics of multi-drug resistantJournal of medicine and life · 2024Article
- Phenotypic and Genotypic Characterization of Extended Spectrum Beta-Lactamase-Producing Clinical Isolates ofInternational journal of microbiology · 2024Article
- An Overview of Antimicrobial Resistance in Saudi Arabia (2013-2023) and the Need for National Surveillance.Microorganisms · 2023Review
- A Narrative Review of Healthcare-Associated Gram-Negative Infections Among Pediatric Patients in Middle Eastern Countries.Infectious diseases and therapy · 2023Review
- Molecular interaction of a putative inhibitor with bacterial SHV, an enzyme associated with antibiotic resistance.Royal Society open science · 2023Article
- Prevalence and Risk Factors Associated with Multidrug Resistance and Extended-SpectrumAntibiotics (Basel, Switzerland) · 2023Article
- Extended Spectrum- and Carbapenemase-Based β-Lactam Resistance in the Arabian Peninsula-A Descriptive Review of Recent Years.Antibiotics (Basel, Switzerland) · 2022Review
- MALDI-TOF MS for Rapid Analysis of Bacterial Pathogens Causing Urinary Tract Infections in the Riyadh Region.Diseases (Basel, Switzerland) · 2022Article
- The Prevalence of Multidrug-ResistantHealthcare (Basel, Switzerland) · 2022Article
- Molecular Characterization of Extended Spectrum β-Lactamase (ESBL) and Virulence Gene-Factors in UropathogenicAntibiotics (Basel, Switzerland) · 2022Article
- Bacterial Community and Genomic Analysis of Carbapenem-ResistantPharmaceuticals (Basel, Switzerland) · 2022Article
- Emergence ofExperimental and therapeutic medicine · 2021Article
- Identification of metallo-β-lactamases and AmpC production among Escherichia coli strains isolated from hemodialysis patients with urinary tract infection.Molecular biology reports · 2021Article
- "Occurrence ofSaudi journal of biological sciences · 2021Article
- Socioeconomic Factors Contributing to Antibiotic Resistance in China: A Panel Data Analysis.Antibiotics (Basel, Switzerland) · 2021Article
- High Throughput Virtual Screening and Molecular Dynamics Simulation for Identifying a Putative Inhibitor of Bacterial CTX-M-15.Antibiotics (Basel, Switzerland) · 2021Article
- Distribution of Extended-Spectrum β-Lactamase (ESBL)-Encoding Genes among Multidrug-Resistant Gram-Negative Pathogens Collected from Three Different Countries.Antibiotics (Basel, Switzerland) · 2021Article
- Pet and Stray Dogs as Reservoirs of Antimicrobial-ResistantInternational journal of microbiology · 2021Article
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13 authors.
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Abstract
The goal of this study was to genotypically characterize extended-spectrum β-lactamase-producing Escherichia coli isolates from the western region of Saudi Arabia and to identify active antibiotics against these isolates using phenotypic and molecular modeling. In total, 211 ESBL-producing E. coli isolates recovered from heterogeneous clinical specimens were identified by MALDI-TOF. Thirty-two sequence types (STs) were identified from a multilocus sequence typing (MLST) analysis of ESBL-producing E. coli, including a novel ST (ST8162). The most common ST in the Saudi and expatriate population was ST131, followed by ST38. All the isolates were multidrug resistant (MDR), and >95% of the isolates were resistant to third-generation (ceftriaxone and ceftazidime) and fourth-generation (cefepime) cephalosporins. The ESBL-positive E. coli isolates primarily harbored the bla
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