ArticleScientific reports2018
Continuous theta-burst stimulation over the dorsolateral prefrontal cortex inhibits improvement on a working memory task.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04864080 (Transdiagnostic Cognitive Biomarkers), which is not on this map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Transdiagnostic Cognitive Biomarkers
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Cognitive Effects Following Offline High-Frequency Repetitive Transcranial Magnetic Stimulation (HF-rTMS) in Healthy Populations: A Systematic Review and Meta-Analysis.Neuropsychology review · 2024Pooled it
- Assessing the Effects of Continuous Theta Burst Stimulation Over the Dorsolateral Prefrontal Cortex on Human Cognition: A Systematic Review.Frontiers in integrative neuroscience · 2020Pooled it
- Non-invasive Brain Stimulation in Alzheimer's Disease and Mild Cognitive Impairment-A State-of-the-Art Review on Methodological Characteristics and Stimulation Parameters.Frontiers in human neuroscience · 2020Pooled it
- Exploring the predictive power of iTBS induced prefrontal excitability using concurrent TBS/fNIRS.Scientific reports · 2025Trial
- Intermittent theta burst stimulation over the parietal cortex has a significant neural effect on working memory.Human brain mapping · 2022Trial
- Efficacy of 5-Hz Transcranial Magnetic Stimulation Over the Left Dorsolateral Prefrontal Cortex in Improving Cognitive Function During the Recovery Phase of Stroke.Brain and behavior · 2026Article
- Neuromodulation of Working Memory: Mechanisms, Targets, and Behavioral Outcomes.Neuroscience insights · 2026Review
- Article
- Intermittent theta burst stimulation (iTBS) and inhibitory control training to reduce binge eating: study protocol for a randomized controlled trial (Be-Nemoic).Frontiers in psychology · 2026Article
- The Philadelphia Theta Burst Project: A novel fMRI-guided electric field modeling dataset with reliability metrics.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Assessing the attentional demand: improvements to the experimental protocol and possible learning effects.Frontiers in psychology · 2025Article
- A causal role of the right dorsolateral prefrontal cortex in random exploration.Scientific reports · 2024Article
- Effect of continuous theta burst stimulation on the glymphatic system, brain network and cognitive function in patients with cerebral small vessel disease.Frontiers in human neuroscience · 2024Article
- The Effect of Continuous Theta Burst Stimulation over the Right Dorsolateral Prefrontal Cortex on Cognitive Function and Emotional Regulation in Patients with Cerebral Small Vessel Disease.Brain sciences · 2023Article
- Synaptic plasticity and mental health: methods, challenges and opportunities.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Review
- Enhancing Visuospatial Working Memory Performance Using Intermittent Theta-Burst Stimulation Over the Right Dorsolateral Prefrontal Cortex.Frontiers in human neuroscience · 2022Article
- Spinal cord representation of motor cortex plasticity reflects corticospinal tract LTP.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- No evidence for changes in GABA concentration, functional connectivity, or working memory following continuous theta burst stimulation over dorsolateral prefrontal cortex.Neuroimage. Reports · 2021Article
- Mapping cognitive brain functions at scale.NeuroImage · 2021Article
- The Role of the Dorsolateral Prefrontal Cortex for Speech and Language Processing.Frontiers in human neuroscience · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Theta-burst stimulation (TBS) over the dorsolateral prefrontal cortex (DLPFC) may be more effective for modulating cortical excitability compared to standard repetitive transcranial magnetic stimulation. However, the impact of intermittent (iTBS) and continuous TBS (cTBS) on working memory (WM) is poorly studied. The aim of our study was to compare the effects of iTBS and cTBS on WM over the left and right DLPFC. iTBS, cTBS or sham stimulation was administered over the right and left hemisphere of fifty-one healthy human subjects. WM was assessed before and after TBS using the 1-back, 2-back, and 3-back tasks. We found classical practice effects in the iTBS and the sham group: WM performance improved following stimulation as measured by the discriminability index. However, this effect could not be observed in the cTBS group. We did not find any hemisphere-dependent effects, suggesting that the practice effect is not lateralized, and TBS affects WM performance in a comparable manner if administered either over the left or the right hemisphere. We propose that our findings represent a useful addition to the literature of TBS-induced effects on WM. Moreover, these results indicate the possibility of clarifying processes underlying WM performance changes by using non-invasive brain stimulation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.