Evidence map›Paper›PMID 30287853›Full record

ArticleScientific reports2018

Calcineurin B homologous protein 3 binds with high affinity to the CHP binding domain of the human sodium/proton exchanger NHE1.

Simon Fuchs, Sierra C Hansen, Marie Markones, Evgeny V Mymrikov, Heiko Heerklotz, Carola Hunte

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Simon FuchsInstitute for Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, D-79104, Freiburg, Germany.
Sierra C HansenInstitute for Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, D-79104, Freiburg, Germany.
Marie MarkonesDepartment of Pharmaceutical Technology and Biopharmacy, University of Freiburg, D-79104, Freiburg, Germany.
Evgeny V MymrikovInstitute for Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, D-79104, Freiburg, Germany.ORCID http://orcid.org/0000-0003-4817-6278
Heiko HeerklotzDepartment of Pharmaceutical Technology and Biopharmacy, University of Freiburg, D-79104, Freiburg, Germany.
Carola HunteInstitute for Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, D-79104, Freiburg, Germany. carola.hunte@biochemie.uni-freiburg.de.ORCID http://orcid.org/0000-0002-0826-3986

Funding

Training Program in Cell, Molecular, and Developmental BiologyT32GM008111 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI YODER, BRADLEY K. · 1985 to 2022
$5.4M
NIGMS NIH HHS T32 GM008111
6 · The paper itself

Abstract

The Na

Indexed as

Binding SitesCalcium-Binding ProteinsCalmodulinCalorimetryChromatography, GelHumansKineticsProtein BindingProtein Interaction MappingSodium-Hydrogen Exchanger 1Calcium-Binding ProteinsCalmodulinSLC9A1 protein, humanSodium-Hydrogen Exchanger 1TESC protein, human

Identifiers

PMID30287853
PMCPMC6172220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.