Evidence map›Paper›PMID 30287735›Full record

ArticleAntioxidants (Basel, Switzerland)2018

Effects of Astaxanthin on the Proliferation and Migration of Breast Cancer Cells In Vitro.

Buckley McCall, Connor K McPartland, Reece Moore, Anastasia Frank-Kamenetskii, Brian W Booth

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 112 citations in OpenAlex.

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  16. Red Swamp Crayfish (Foods (Basel, Switzerland) · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Buckley McCallDepartment of Biological Sciences, Clemson University, Clemson, SC 29634, USA. mccbuc@gmail.com.
Connor K McPartlandDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA. cmcpart@g.clemson.edu.ORCID 0000-0002-9717-0924
Reece MooreDepartment of Biological Sciences, Clemson University, Clemson, SC 29634, USA. reece5@g.clemson.edu.
Anastasia Frank-KamenetskiiDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA. afrankk@g.clemson.edu.
Brian W BoothDepartment of Bioengineering, Clemson University, Clemson, SC 29634, USA. brbooth@clemson.edu.ORCID 0000-0003-2542-7302
Clemson University · US

Funding

ACCAC N/A
6 · The paper itself

Abstract

Astaxanthin (ASX) is a marine-based ketocarotenoid; an accessory pigment in plants in that it has many different potential functions. ASX is an antioxidant that is notably more potent than many other antioxidants. Antioxidants have anti-inflammatory and oxidative stress-reducing properties to potentially reduce the incidence of cancer or inhibit the expansion of tumor cells. In this study, we tested the hypothesis that ASX would inhibit proliferation and migration of breast cancer cells in vitro. We found that application of ASX significantly reduced proliferation rates and inhibited breast cancer cell migration compared to control normal breast epithelial cells. Based on these results, further investigation of the effects of ASX on not only breast cancer cells, but other forms of tumor cells, should be carried out.

Indexed as

antioxidantastaxanthinbreast cancercarotenoidmigrationproliferationXanthoph

Identifiers

PMID30287735
PMCPMC6210693
OpenAlexW2894746403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.