Evidence map›Paper›PMID 30287684›Full record

ArticleThe Journal of biological chemistry2018

The atlastin membrane anchor forms an intramembrane hairpin that does not span the phospholipid bilayer.

Miguel A Betancourt-Solis, Tanvi Desai, James A McNew

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Structural and functional characterization of the brain-specific dynamin superfamily member RNF112.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Review
  4. A bird's-eye view of the endoplasmic reticulum in filamentous fungi.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Frontiers in cellular and infection microbiology · 2022
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Frontiers in cell and developmental biology · 2021
    Review
  17. Article
  18. Review
  19. Review
  20. Atlastin-mediated membrane tethering is critical for cargo mobility and exit from the endoplasmic reticulum.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Miguel A Betancourt-SolisFrom the Department of Biochemistry and Cell Biology, Rice University, Houston, Texas 77005.
Tanvi DesaiFrom the Department of Biochemistry and Cell Biology, Rice University, Houston, Texas 77005.
James A McNewFrom the Department of Biochemistry and Cell Biology, Rice University, Houston, Texas 77005 mcnew@rice.edu.ORCID 0000-0001-8459-3664
Rice University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endoplasmic reticulum (ER) is composed of flattened sheets and interconnected tubules that extend throughout the cytosol and makes physical contact with all other cytoplasmic organelles. This cytoplasmic distribution requires continuous remodeling. These discrete ER morphologies require specialized proteins that drive and maintain membrane curvature. The GTPase atlastin is required for homotypic fusion of ER tubules. All atlastin homologs possess a conserved domain architecture consisting of a GTPase domain, a three-helix bundle middle domain, a hydrophobic membrane anchor, and a C-terminal cytosolic tail. Here, we examined several

Indexed as

Lipid BilayersMembrane FusionAnimalsDrosophila ProteinsEndoplasmic ReticulumGTP-Binding ProteinsGTP PhosphohydrolasesGuanosine TriphosphateHumansHydrophobic and Hydrophilic InteractionsMembrane ProteinsPhospholipidsProtein DomainsATL1 protein, humanatl protein, DrosophilaDrosophila ProteinsGTP-Binding ProteinsGTP PhosphohydrolasesGuanosine TriphosphateLipid BilayersMembrane ProteinsPhospholipidscell compartmentalizationendoplasmic reticulum (ER)FRETGTPaseintramembrane hairpin loopmembrane fusionneurodegenerationphospholipid vesicleSPG3Atransmembrane domain

Identifiers

PMID30287684
PMCPMC6290144
OpenAlexW2895030959

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.