Evidence map›Paper›PMID 30287681›Full record

ArticleMolecular systems biology2018

tRNA epitranscriptomics and biased codon are linked to proteome expression in

Chee Sheng Ng, Ameya Sinha, Yaw Aniweh, Qianhui Nah, Indrakanti Ramesh Babu, Chen Gu, Yok Hian Chionh, Peter C Dedon, Peter R Preiser

Open access · goldAbstract read
In one paragraph

Article in Molecular systems biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
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  5. tRNA modifying enzymes MnmE and MnmG are essential forbioRxiv : the preprint server for biology · 2025
    Article
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  14. TheeLife · 2023
    Article
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  16. Review
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  19. Arsenite toxicity is regulated by queuine availability and oxidation-induced reprogramming of the human tRNA epitranscriptome.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  20. The first apicoplast tRNA thiouridylase plays a vital role in the growth ofFrontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Chee Sheng NgAntimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, Singapore City, Singapore.
Ameya SinhaAntimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, Singapore City, Singapore.ORCID 0000-0001-7959-075X
Yaw AniwehSchool of Biological Sciences, Nanyang Technological University, Singapore City, Singapore.
Qianhui NahAntimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, Singapore City, Singapore.
Indrakanti Ramesh BabuDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Chen GuDepartment of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Yok Hian ChionhAntimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, Singapore City, Singapore.
Peter C DedonAntimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, Singapore City, Singapore pcdedon@mit.edu prpreiser@ntu.edu.sg.ORCID 0000-0003-0011-3067
Peter R PreiserAntimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, Singapore City, Singapore pcdedon@mit.edu prpreiser@ntu.edu.sg.ORCID 0000-0003-4331-7000
Nanyang Technological University · SGMassachusetts Institute of Technology · USCenter for Environmental Health · USNational University of Singapore · SGSingapore-MIT Alliance for Research and Technology · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among components of the translational machinery, ribonucleoside modifications on tRNAs are emerging as critical regulators of cell physiology and stress response. Here, we demonstrate highly coordinated behavior of the repertoire of tRNA modifications of

Indexed as

CodonEpigenesis, GeneticErythrocytesGene Expression ProfilingGene Expression RegulationHumansPlasmodium falciparumProtein BiosynthesisProtein Processing, Post-TranslationalProteomicsProtozoan ProteinsRNA, TransferCodonProtozoan ProteinsRNA, TransferPlasmodium falciparumquantitative proteomicstRNA modifications

Identifiers

PMID30287681
PMCPMC6171970
OpenAlexW2895693119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.