Evidence map›Paper›PMID 30287481›Full record

ArticleRNA (New York, N.Y.)2019

Rare variants of the FMN riboswitch class in

Ruben M Atilho, Kevin R Perkins, Ronald R Breaker

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. The current riboswitch landscape inMicrobiology (Reading, England) · 2024
    Review
  4. Article
  5. 8-oxoguanine riboswitches in bacteria detect and respond to oxidative DNA damage.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Article
  7. Variants of the guanine riboswitch class exhibit altered ligand specificities for xanthine, guanine, or 2'-deoxyguanosine.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Evidence that theRNA (New York, N.Y.) · 2019
    Article
  14. Article
  15. Regulation of Bacterial Gene Expression by Transcription Attenuation.Microbiology and molecular biology reviews : MMBR · 2019
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ruben M Atilho *Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520-8103, USA.
Kevin R Perkins *Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut 06520-8103, USA.
Ronald R BreakerDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520-8103, USA.
Yale University · USHoward Hughes Medical Institute · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007205 · NIGMS · YALE UNIVERSITY · PI KAZMIERCZAK, BARBARA I · 1985 to 2019
$42.9M
X-RAY ANALYSIS OF PROTEIN STRUCTURE AND FUNCTIONP01GM022778 · NIGMS · YALE UNIVERSITY · PI BREAKER, RONALD R · 1985 to 2019
$26.1M
NIGMS NIH HHS P01 GM022778NIGMS NIH HHS T32 GM007205NIH HHS GM022778NIH HHS T32 GM007205
6 · The paper itself

Abstract

Many bacteria use flavin mononucleotide (FMN) riboswitches to control the expression of genes responsible for the biosynthesis and transport of this enzyme cofactor or its precursor, riboflavin. Rare variants of FMN riboswitches found in strains of

Indexed as

Base SequenceClostridioides difficileFlavin-Adenine DinucleotideFlavin MononucleotideGenetic VariationLigandsModels, MolecularMutationNucleic Acid ConformationPhotolysisRiboswitchRNA, BacterialSpecies SpecificityFlavin-Adenine DinucleotideFlavin MononucleotideLigandsRiboswitchRNA, Bacterialaptamerflavin mononucleotidelumichromelumiflavinnoncoding RNAriboflavin biosynthesis

Identifiers

PMID30287481
PMCPMC6298564
OpenAlexW2894943551

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.