Evidence map›Paper›PMID 30287473›Full record

ArticleThe European respiratory journal2018

The cystic fibrosis airway milieu enhances rescue of F508del in a pre-clinical model.

Martina Gentzsch, Deborah M Cholon, Nancy L Quinney, Susan E Boyles, Mary E B Martino, Carla M P Ribeiro

Abstract readLetter
In one paragraph

Article in The European respiratory journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Genetic and chemical correction of cystic fibrosis reduces airway susceptibility to SARS-CoV-2.American journal of physiology. Lung cellular and molecular physiology · 2026
    Article
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  5. Article
  6. Review
  7. Article
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  13. Airway Epithelial InflammationFrontiers in pharmacology · 2021
    Article
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Martina GentzschMarsico Lung Institute and Cystic Fibrosis Research Center, Chapel Hill, NC, USA.
Deborah M CholonMarsico Lung Institute and Cystic Fibrosis Research Center, Chapel Hill, NC, USA.
Nancy L QuinneyMarsico Lung Institute and Cystic Fibrosis Research Center, Chapel Hill, NC, USA.
Susan E BoylesMarsico Lung Institute and Cystic Fibrosis Research Center, Chapel Hill, NC, USA.
Mary E B MartinoMarsico Lung Institute and Cystic Fibrosis Research Center, Chapel Hill, NC, USA.
Carla M P RibeiroMarsico Lung Institute and Cystic Fibrosis Research Center, Chapel Hill, NC, USA.

Funding

Vector CoreP30DK065988 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Richard Charles Boucher, Martina Gentzsch · 2004 to 2026
$26.5M
Rescued CFTR Function in Preclinical Models of Airway Epithelial InflammationR56HL136733 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GENTZSCH, MARTINA, RIBEIRO, CARLA MARIA PEDROSA · 2018 to 2018
$428k
NHLBI NIH HHS R56 HL136733NIDDK NIH HHS P30 DK065988
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AminophenolsAminopyridinesBenzodioxolesBronchiCell LineColforsinCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorEpithelial CellsHumansInflammationMutationQuinolonesRespiratory SystemAminophenolsAminopyridinesBenzodioxolesColforsinCystic Fibrosis Transmembrane Conductance Regulatorcystic fibrosis transmembrane conductance regulator delta F508ivacaftorlumacaftorQuinolones

Identifiers

PMID30287473
PMCPMC6482470

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.