Evidence map›Paper›PMID 30287245›Full record

SynthesisNeuroscience and biobehavioral reviews2018

Audiovisual multisensory integration in individuals with autism spectrum disorder: A systematic review and meta-analysis.

Jacob I Feldman, Kacie Dunham, Margaret Cassidy, Mark T Wallace, Yupeng Liu, Tiffany G Woynaroski

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Neuroscience and biobehavioral reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed, 4 pooled it
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 4 syntheses or guidelines pooled it, 188 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Intact Visual Correlation Detection in Autistic Adults.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  7. Staged Audiovisual Speech Integration and Altered Early-Stage Audiovisual Processing in Autistic Children: An EEG Investigation.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Relations Between Preferential Looking to Synchronous Audiovisual Speech and Expressive Language in Infants With Autistic and Non-Autistic Siblings.Mind, brain and education : the official journal of the International Mind, Brain, and Education Society · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Intact Audiovisual Spatial Integration in Autistic Children.Journal of autism and developmental disorders · 2025
    Article
  19. Article
  20. Article

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jacob I FeldmanDepartment of Hearing and Speech Sciences, Vanderbilt University, 1215 21st Ave S, MCE South Tower 8310, Nashville, TN, 37232, USA. Electronic address: jacob.i.feldman@vanderbilt.edu.
Kacie DunhamNeuroscience Undergraduate Program, Vanderbilt University, Nashville, TN, USA.
Margaret CassidyNeuroscience Undergraduate Program, Vanderbilt University, Nashville, TN, USA.
Mark T WallaceDepartment of Psychology, Vanderbilt University, Nashville, TN, USA; Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Pharmacology, Vanderbilt University, Nashville, TN, USA; Vanderbilt Kennedy Center, Vanderbilt University Medical Center, 110 Magnolia Cir, Nashville, TN, 37203, USA; Vanderbilt Brain Institute, Vanderbilt University, 465 21st Avenue South, Nashville, TN, 37232, USA; Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, 1215 21st Ave S, MCE South Tower 8310, Nashville, TN, 27323, USA. Electronic address: mark.wallace@vanderbilt.edu.
Yupeng LiuNeuroscience Undergraduate Program, Vanderbilt University, Nashville, TN, USA.
Tiffany G WoynaroskiVanderbilt Kennedy Center, Vanderbilt University Medical Center, 110 Magnolia Cir, Nashville, TN, 37203, USA; Vanderbilt Brain Institute, Vanderbilt University, 465 21st Avenue South, Nashville, TN, 37232, USA; Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, 1215 21st Ave S, MCE South Tower 8310, Nashville, TN, 27323, USA. Electronic address: tiffany.g.woynaroski@vanderbilt.edu.
Vanderbilt University · US

Funding

Institutional Career Development CoreKL2TR002245 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Julie A. Bastarache · 2017 to 2026
$9.3M
Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CUTTING, LAURIE E · 2015 to 2019
$7.1M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)KL2TR000446 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$2.8M
Sensory Project in Infant/Toddler Siblings of Children with Autism (Project SPIS)R21DC016144 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WOYNAROSKI, TIFFANY · 2017 to 2019
$474k
NCATS NIH HHS KL2 TR000446NCATS NIH HHS KL2 TR002245NICHD NIH HHS U54 HD083211NIDCD NIH HHS R21 DC016144
6 · The paper itself

Abstract

An ever-growing literature has aimed to determine how individuals with autism spectrum disorder (ASD) differ from their typically developing (TD) peers on measures of multisensory integration (MSI) and to ascertain the degree to which differences in MSI are associated with the broad range of symptoms associated with ASD. Findings, however, have been highly variable across the studies carried out to date. The present work systematically reviews and quantitatively synthesizes the large literature on audiovisual MSI in individuals with ASD to evaluate the cumulative evidence for (a) group differences between individuals with ASD and TD peers, (b) correlations between MSI and autism symptoms in individuals with ASD and (c) study level factors that may moderate findings (i.e., explain differential effects) observed across studies. To identify eligible studies, a comprehensive search strategy was employed using the ProQuest search engine, PubMed database, forwards and backwards citation searches, direct author contact, and hand-searching of select conference proceedings. A significant between-group difference in MSI was evident in the literature, with individuals with ASD demonstrating worse audiovisual integration on average across studies compared to TD controls. This effect was moderated by mean participant age, such that between-group differences were more pronounced in younger samples. The mean correlation between MSI and autism and related symptomatology was also significant, indicating that increased audiovisual integration in individuals with ASD is associated with better language/communication abilities and/or reduced autism symptom severity in the extant literature. This effect was moderated by whether the stimuli were linguistic versus non-linguistic in nature, such that correlation magnitudes tended to be significantly greater when linguistic stimuli were utilized in the measure of MSI. Limitations and future directions for primary and meta-analytic research are discussed.

Indexed as

Auditory PerceptionAutism Spectrum DisorderVisual PerceptionHumansAudiovisualAutismMeta-analysisMultisensory integrationSensory

Identifiers

PMID30287245
PMCPMC6291229
OpenAlexW2895513670

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.