Evidence map›Paper›PMID 30287068›Full record

ArticleThe Journal of pediatrics2018

Role of Genetic Susceptibility in the Development of Bronchopulmonary Dysplasia.

Richard B Parad, Abigail B Winston, Leslie A Kalish, Munish Gupta, Ivana Thompson, Yvonne Sheldon, Joann Morey, Linda J Van Marter

Open access · greenAbstract read
In one paragraph

Article in The Journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Bronchopulmonary Dysplasia: Then, Now, and Next.Pediatric allergy, immunology, and pulmonology · 2020
    Review
  9. Bronchopulmonary dysplasia.Nature reviews. Disease primers · 2019
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Richard B ParadBrigham and Women's Hospital, Boston, MA; Boston Children's Hospital, Boston, MA; Harvard Medical School, Boston, MA. Electronic address: rparad@bwh.harvard.edu.
Abigail B WinstonBrigham and Women's Hospital, Boston, MA.
Leslie A KalishBoston Children's Hospital, Boston, MA; Harvard Medical School, Boston, MA.
Munish GuptaBoston Children's Hospital, Boston, MA; Harvard Medical School, Boston, MA; Beth Israel Deaconess Medical Center, Boston, MA.
Ivana ThompsonVanderbilt University Medical Center, Nashville, TN.
Yvonne SheldonBrigham and Women's Hospital, Boston, MA.
Joann MoreyBrigham and Women's Hospital, Boston, MA.
Linda J Van MarterBrigham and Women's Hospital, Boston, MA; Boston Children's Hospital, Boston, MA; Harvard Medical School, Boston, MA.
Brigham and Women's Hospital · USBoston Children's Hospital · USVanderbilt University Medical Center · US

Funding

The Harvard Clinical and Translational Science CenterUL1TR002541 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2018 to 2022
$93.0M
HARVARD CLINICAL AND TRANSLATIONAL SCIENCE CENTER (UL1)UL1RR025758 · NCRR · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2008 to 2011
$91.4M
Neonatal Biomarkers in Extremely Preterm Babies Predict Childhood Brain DisordersU01NS040069 · NINDS · CHILDREN'S HOSPITAL BOSTON · PI KUBAN, KARL · 2001 to 2014
$34.0M
SYNAPTIC MECHANISMS IN HIPPOCAMPAL EPILEPTOGENESISP30HD018655 · NICHD · CHILDREN'S HOSPITAL BOSTON · PI POMEROY, SCOTT LOREN · 1985 to 2015
$26.2M
Genome Sequence-Based Screening for Childhood Risk and Newborn IllnessU19HD077671 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI BEGGS, ALAN H., GREEN, ROBERT C. · 2013 to 2018
$6.1M
CHANNEL-MEDIATED RBC DEHYDRATION IN SICKLE CELL DISEASEK01HL067699 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI RIVERA, ALICIA · 2001 to 2003
$417k
NCATS NIH HHS UL1 TR002541NCRR NIH HHS UL1 RR025758NHLBI NIH HHS K01 HL067699NICHD NIH HHS P30 HD018655NICHD NIH HHS U19 HD077671NINDS NIH HHS U01 NS040069
6 · The paper itself

Abstract

objectiveTo assess heritable contributions to bronchopulmonary dysplasia (BPD) risk in a twin cohort restricted to gestational age at birth <29 weeks. STUDY

designA total of 250 twin pairs (192 dichorionic, 58 monochorionic) born <29 weeks gestational age with known BPD status were identified. Three statistical methods applicable to twin cohorts (χ

resultsχ

conclusionsOur analysis suggests that heritability is not a major contributor to BPD risk in preterm infants <29 weeks gestational age.

Indexed as

Cause of DeathInfant, Extremely PrematureTwin Studies as TopicBostonBronchopulmonary DysplasiaCohort StudiesDatabases, FactualFemaleGenetic Predisposition to DiseaseGestational AgeHumansInfant, NewbornMalePregnancyPregnancy, TwinPrevalenceACE modelingbronchopulmonary dysplasiadisease riskextremely low gestational age newbornsgeneticsheritabilitytwin study

Identifiers

PMID30287068
PMCPMC8516345
OpenAlexW2895095426

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.