Evidence map›Paper›PMID 30286790›Full record

ArticleBMC research notes2018

Lessons from a comparison of immuno-chromatographic and chemiluminescent micro-particle immunoassay in the diagnosis of syphilis.

Sepiso K Masenga, Mercy Mweemba, Annie Kachele, Yahns Chalubemba, Paul Toloka, Benson M Hamooya

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sepiso K MasengaPathology Laboratory Department, Research Section, Livingstone Central Hospital, Akapelwa Street, P.O. Box 60091, Livingstone, Zambia. sepisomasenga@gmail.com.
Mercy MweembaChikankata College of Biomedical Sciences, Private Bag Sector 2, Mazabuka, Zambia.
Annie KachelePathology Laboratory Department, Research Section, Livingstone Central Hospital, Akapelwa Street, P.O. Box 60091, Livingstone, Zambia.
Yahns ChalubembaPathology Laboratory Department, Research Section, Livingstone Central Hospital, Akapelwa Street, P.O. Box 60091, Livingstone, Zambia.
Paul TolokaPathology Laboratory Department, Research Section, Livingstone Central Hospital, Akapelwa Street, P.O. Box 60091, Livingstone, Zambia.
Benson M HamooyaPathology Laboratory Department, Research Section, Livingstone Central Hospital, Akapelwa Street, P.O. Box 60091, Livingstone, Zambia.
University of Zambia · ZM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo synthesize lessons from comparison of results obtained from the immuno-chromatographic SD Bioline testing method and the chemiluminescent micro-particle immunoassay Architect in the diagnosis of syphilis at Livingstone Central hospital laboratory.

resultsThe specificity and sensitivity of SD Bioline syphilis 3.0 against the chemiluminescent immunoassay using the Architect syphilis Treponema pallidum (TP) was 85.3% and 91.3% respectively with substantial agreement between the two test methods (88%, ĸ  = 0.76; p < 0.0005). We recommend further comprehensive study with a larger sample size and clinical details to ascertain the validity of our findings. We also recommend using a non-treponemal test with the current treponemal tests being used to aid diagnosis.

Indexed as

Antibodies, BacterialChromatographyHumansImmunoassayLuminescent MeasurementsSensitivity and SpecificitySyphilisSyphilis SerodiagnosisTreponema pallidumAntibodies, BacterialArchitect syphilisImmunoassaySD BiolineTreponema pallidum

Identifiers

PMID30286790
PMCPMC6172779
OpenAlexW2894948582

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.