ArticleWorld journal of surgical oncology2018
Prognostic significance of metastatic lymph node ratio: the lymph node ratio could be a prognostic indicator for patients with gastric cancer.
Article in World journal of surgical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Trial
- Prognostic impact of lymph node ratio after suboptimal lymphadenectomy in gastric cancer: a retrospective cohort study with interaction analysis.World journal of surgical oncology · 2026Article
- Evaluation of lymph node ratios and log odds of positive nodes as prognostic indicators in primary organ malignancy.Medical journal, Armed Forces India · 2025Article
- A prognostic nomogram utilized lymph node ratio for signet ring cell gastric cancer patients post-surgery.Journal of gastrointestinal oncology · 2025Article
- Article
- Preoperative prognostic assessment using intratumoral and peritumoral adipose tissue radiomics derived from contrast-enhanced CT in cT3-4 gastric cancer.Frontiers in oncology · 2025Article
- Clinicopathologic characteristics and predictive nomogram of skip lymph node metastasis in gastric cancer.Frontiers in oncology · 2025Article
- Positive Lymph Node Ratio as a new prognostic score in Geriatric patients with operated gastric cancer.Heliyon · 2024Article
- Comparison of the predictive performance of three lymph node staging systems for late-onset gastric cancer patients after surgery.Frontiers in surgery · 2024Article
- Prognostic significance of metastatic lymph node ratio in gastric cancer: a Western-center analysis.BMC surgery · 2023Article
- Surgeon-Pathologist Team Approach Dramatically Affects Lymph Nodes Detection and Improves Patients' Short-Term Outcome.Cancers · 2022Article
- Does lymph node ratio (metastasis/total lymph node count) affect survival and prognosis in gastric cancer?Saudi medical journal · 2022Article
- Machine Learning-Based Prediction of Lymph Node Metastasis Among Osteosarcoma Patients.Frontiers in oncology · 2022Article
- The Prognostic Value of Lymph Node Ratio after Neoadjuvant Chemotherapy in Patients with Locally Advanced Gastric Adenocarcinoma.Journal of gastric cancer · 2021Article
- Accurate Risk Stratification of Patients with Node-Positive Gastric Cancer by Lymph Node Ratio.World journal of surgery · 2020Article
- Preoperative prealbumin levels on admission as an independent predictive factor in patients with gastric cancer.Medicine · 2020Article
- "D2 plus" lymphadenectomy is associated with improved survival in distal gastric cancer with clinical serosa invasion: a propensity score analysis.Scientific reports · 2019Article
- Lymph Node Yield Following Packet Submission After Isolation By Surgeon During Gastrectomy.Cancer management and research · 2019Article
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundTo demonstrate the prognostic significance and value of lymph node ratio (LNR) and evaluate the possibility of becoming a new indicator to enhance the current Union for International Cancer Control (UICC)/American Joint Committee on Cancer (AJCC) tumor, lymph node, metastasis (TNM) staging system.
methodsOur retrospective study included 221 patients who got gastric cancer and underwent curative gastrectomy between 2005 and 2012 at the Fourth Hospital Affiliated of China Medical University. The log-rank test was used to compare the clinicopathological variables. The Kaplan-Meier method and Cox proportional hazard regression model was used to perform the univariate analysis and multivariate statistical survival analysis.
resultsThe patients with a better differentiated pathological type; an earlier stage of T staging, N staging, and TNM staging; and a lesser LNR would have a longer survival time according to the univariate analysis. As for the multivariate analysis, the Grade, T stage, N stage, and LNR had the statistical significance. Both in group 1 (the number of lymph nodes examined ≥ 15, namely LN ≥ 15) and group 2 (LN < 15), the LNR had statistical significance and the median survival time would decrease with the increase of the LNR. It was still statistically significant between group LNR1 and group LNR2 which were regrouped by the new cut-off value.
conclusionThe LNR could estimate the prognosis of patients with curative gastrectomy regardless of the number of lymph nodes examined. Thus LNR could become a new indicator to enhance the current TNM stage system.
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