Evidence map›Paper›PMID 30285906›Full record

ArticleParasites & vectors2018

Spatial distribution and populations at risk of A. lumbricoides and T. trichiura co-infections and infection intensity classes: an ecological study.

Kei Owada, Colleen L Lau, Lydia Leonardo, Archie C A Clements, Laith Yakob, Mark Nielsen, Hélène Carabin, Ricardo J Soares Magalhães

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In one paragraph

Article in Parasites & vectors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  10. Whipworm and roundworm infections.Nature reviews. Disease primers · 2020
    Review
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  12. Article
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  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kei OwadaSchool of Medicine, The University of Queensland, QLD, South Brisbane, Australia. kei.owada@uqconnect.edu.au.ORCID http://orcid.org/0000-0002-4274-2059
Colleen L LauChildren's Health and Environment Program, Child Health Research Centre, The University of Queensland, QLD, South Brisbane, Australia.
Lydia LeonardoDepartment of Parasitology, College of Public Health, University of the Philippines Manila, Manila, Philippines.
Archie C A ClementsResearch School of Population Health, Australian National University, ACT, Canberra, Australia.
Laith YakobDepartment of Disease Control, London School of Hygiene and Tropical Medicine, London, UK.
Mark NielsenSchool of Psychology, The University of Queensland, QLD, St Lucia, Australia.
Hélène CarabinDepartment of Biostatistics and Epidemiology, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma, USA.
Ricardo J Soares MagalhãesChildren's Health and Environment Program, Child Health Research Centre, The University of Queensland, QLD, South Brisbane, Australia.

Funding

ECOLOGY AND TRANSMISSION OF S.JAPONICUM: PHILIPPINESR01TW001582 · FIC · BROWN UNIVERSITY · PI MCGARVEY, STEPHEN T. · 2000 to 2004
$1.7M
FIC NIH HHS R01 TW001582Wellcome Trust
6 · The paper itself

Abstract

backgroundSoil-transmitted helminth (STH) infections are highly prevalent in the Philippines. Mapping the prevalence and high-intensity of STH co-infections can help guide targeted intervention programmes to reduce morbidity, especially among vulnerable school-aged children. In this study, we aimed to predict the spatial distribution of the prevalence of Ascaris lumbricoides and Trichuris trichiura co-infection and infection intensity classes in the Philippines to identify populations most in need of interventions.

methodsData on STH infections from 29,919 individuals during the nationwide parasitological survey in 2005 to 2007 were included in the analysis. To geographically predict the prevalence of A. lumbricoides and T. trichiura co-infections and infection intensity classes, Bayesian multinomial geostatistical models were built including age, sex, environmental variables and a geostatistical random effect. The number of individuals co-infected and belonging to each of the infection intensity classes in 2017 was forecast by combining our predictive prevalence maps with population density maps.

resultsOur models showed that school-aged children (5-19 years) are most at risk of A. lumbricoides and T. trichiura co-infections and of moderate/high infection intensity compared to other age groups. We identified target provinces where the likelihood of STH-associated morbidity was highest: Luzon (Bulacan, Benguet, Cavite, Sorsogon, Metropolitan Manila, Pampanga and Rizal), the Visayas (Cebu, Iloilo, Leyte and Negros Occidental), and in Mindanao (Agusan Del Norte, Davao Del Sur, Davao Oriental, Lanao Del Sur, Maguindanao, Misamis Oriental, Sulu and Zamboanga Del Sur). Luzon had the highest estimated number of school-aged children with A. lumbricoides and T. trichiura co-infections (estimated total 89,400), followed by the Visayas (38,300) and Mindanao (20,200).

conclusionsOur study provided epidemiological evidence to highlight national priority areas for controlling co-infections and high intensity infections in the Philippines. Our maps could assist more geographically targeted interventions to reduce the risk of STH-associated morbidity in the Philippines.

Indexed as

EnvironmentAdolescentAdultAnimalsAscariasisChildChild, PreschoolCoinfectionFecesFemaleHelminthsHumansMaleModels, Spatial InteractionPhilippinesPrevalenceSoilAscaris lumbricoidesBayesian geostatisticsCo-infectionInfection intensitySoil-transmitted helminthsSpatial epidemiologyThe PhilippinesTrichuris trichiura

Identifiers

PMID30285906
PMCPMC6171148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.