Evidence map›Paper›PMID 30285714›Full record

ArticleBMC complementary and alternative medicine2018

Protective effects and mechanisms of Terminalia catappa L. methenolic extract on hydrogen-peroxide-induced oxidative stress in human skin fibroblasts.

Ya-Han Huang, Po-Yuan Wu, Kuo-Ching Wen, Chien-Yih Lin, Hsiu-Mei Chiang

Open access · goldAbstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

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  8. Jelly Fig (Antioxidants (Basel, Switzerland) · 2022
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  9. Protective Effect of Djulis (Molecules (Basel, Switzerland) · 2022
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  13. Plants of the GenusFrontiers in pharmacology · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ya-Han HuangDepartment of Cosmeceutics, China Medical University, 91 Hsueh-Shih Road, Taichung, 40402, Taiwan.
Po-Yuan WuDepartment of Dermatology, China Medical University Hospital, Taichung, 40402, Taiwan.
Kuo-Ching WenDepartment of Cosmeceutics, China Medical University, 91 Hsueh-Shih Road, Taichung, 40402, Taiwan.
Chien-Yih LinDepartment of Biotechnology, Asia University, 500 Liufeng Road, Wufeng District, Taichung City, 41354, Taiwan. yihlin@asia.edu.tw.
Hsiu-Mei ChiangDepartment of Cosmeceutics, China Medical University, 91 Hsueh-Shih Road, Taichung, 40402, Taiwan. hmchiang@mail.cmu.edu.tw.
China Medical University · TWAsia University · TWChina Medical University Hospital · TW

Funding

China Medical University (TW) CMU103-ASIA-11China Medical University (TW) CMU105-ASIA-08the Ministry of Science and Technology (TW) MOST 104-2320-B-039-006
6 · The paper itself

Abstract

backgroundOxidative stress plays a crucial role in aging-related phenomenon, including skin aging and photoaging. This study investigated the protective role and possible mechanism of Terminalia catappa L. methanolic extract (TCE) in human fibroblasts (Hs68) against hydrogen peroxide (H

methodsVarious in vitro antioxidant assays were performed in this study. The effect and mechanisms of TCE on oxidative stress-induced oxidative damage were studied by using western blotting.

resultsThe IC

conclusionsAccording to our findings, TCE is a potent antioxidant and protective agent that can be used in antioxidative stress-induced skin aging.

Indexed as

AntioxidantsCell LineFibroblastsHeme Oxygenase-1HumansHydrogen PeroxideMatrix Metalloproteinase 1Matrix Metalloproteinase 3Oxidative StressPlant ExtractsSkinSkin AgingTerminaliaAntioxidantsHeme Oxygenase-1Hydrogen PeroxideMatrix Metalloproteinase 1Matrix Metalloproteinase 3MMP3 protein, humanPlant ExtractsAgingExtracellular matrixHemeoxygenase-1 (HO-1)Oxidative stressReactive oxygen species

Identifiers

PMID30285714
PMCPMC6167875
OpenAlexW2894690055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.