Evidence map›Paper›PMID 30285425›Full record

ArticleBiochemistry2018

Endocannabinoid Virodhamine Is an Endogenous Inhibitor of Human Cardiovascular CYP2J2 Epoxygenase.

Lauren N Carnevale, Andres S Arango, William R Arnold, Emad Tajkhorshid, Aditi Das

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Anthracycline derivatives inhibit cardiac CYP2J2.Journal of inorganic biochemistry · 2022
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

University of Illinois Urbana-Champaign · US

Funding

Synthetic Antigen Binder CoreU54GM087519 · NIGMS · UNIVERSITY OF CHICAGO · PI NAKAMOTO, ROBERT K. · 2010 to 2017
$31.9M
WHOLE CELL SIMULATIONP41GM104601 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI TAJKHORSHID, EMAD · 2012 to 2021
$19.0M
Biochemical Mechanism of Eicosanoid Synthesizing EnzymesR01GM115584 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI DAS, ADITI · 2017 to 2022
$1.7M
Understanding the role of phospholipids in integrin signalingR01GM101048 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SLIGAR, STEPHEN G. · 2012 to 2015
$1.1M
Discovery of omega-3 endocannabinoid epoxides and elucidation of their neuroinflammatory propertiesR03DA042365 · NIDA · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI DAS, ADITI · 2017 to 2018
$143k
NIDA NIH HHS R03 DA042365NIGMS NIH HHS P41 GM104601NIGMS NIH HHS R01 GM101048NIGMS NIH HHS R01 GM115584NIGMS NIH HHS U54 GM087519
6 · The paper itself

Abstract

The human body contains endogenous cannabinoids (endocannabinoids) that elicit effects similar to those of Δ

Indexed as

AnimalsArachidonic AcidsCannabinoid Receptor ModulatorsCannabinoidsCytochrome P-450 CYP2J2Cytochrome P-450 Enzyme SystemEndocannabinoidsHeartHumansHuman Umbilical Vein Endothelial CellsMolecular Docking SimulationPolyunsaturated AlkamidesProtein ConformationSwineWound HealinganandamideArachidonic AcidsCannabinoid Receptor ModulatorsCannabinoidsCYP2J2 protein, humanCytochrome P-450 CYP2J2Cytochrome P-450 Enzyme SystemEndocannabinoidsPolyunsaturated Alkamidesvirodhamine

Identifiers

PMID30285425
PMCPMC6262108
OpenAlexW2894558220

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.