Evidence map›Paper›PMID 30285068›Full record

ArticleAmerican journal of clinical pathology2019

Unexpectedly High Prevalence of Cystoisospora belli Infection in Acalculous Gallbladders of Immunocompetent Patients.

Mushal Noor, Philip J Katzman, Aaron R Huber, Jennifer J Findeis-Hosey, Christa Whitney-Miller, Raul S Gonzalez, Zhongren Zhou, Henriette D N'kodia, Kathryn Skonick, Rebecca L Abell and 3 more

Abstract read
In one paragraph

Article in American journal of clinical pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Mushal NoorDepartment of Pathology, University of Rochester Medical Center, Rochester, NY.
Philip J KatzmanDepartment of Pathology, University of Rochester Medical Center, Rochester, NY.
Aaron R HuberDepartment of Pathology, University of Rochester Medical Center, Rochester, NY.
Jennifer J Findeis-HoseyDepartment of Pathology, University of Rochester Medical Center, Rochester, NY.
Christa Whitney-MillerDepartment of Pathology, University of Rochester Medical Center, Rochester, NY.
Raul S GonzalezDepartment of Pathology, University of Rochester Medical Center, Rochester, NY.
Zhongren ZhouDepartment of Pathology, University of Rochester Medical Center, Rochester, NY.
Henriette D N'kodiaDepartment of Pathology, University of Rochester Medical Center, Rochester, NY.
Kathryn SkonickDepartment of Pathology, University of Rochester Medical Center, Rochester, NY.
Rebecca L AbellDepartment of Pediatrics, University of Rochester Medical Center, Rochester, NY.
Lawrence J SaubermannDepartment of Pediatrics, University of Rochester Medical Center, Rochester, NY.
Laura W LampsDepartment of Pathology, University of Michigan, Ann Arbor.
Michael G DrageDepartment of Pathology, University of Rochester Medical Center, Rochester, NY.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Indications for cholecystectomy have changed dramatically over the past three decades. Cystoisospora belli has been reported in cholecystectomy specimens of immunocompetent patients. The present study was designed to determine the prevalence and clinical association of C belli in the gallbladder. Methods: The study included retrospective review of cholecystectomy specimens (n = 401) removed for various indications, and a prospective cohort of cholecystectomy specimens (n = 22) entirely submitted for histologic evaluation. Correlations of presence of C belli with age, sex, clinical indication, and abnormalities of preoperative laboratory values were assessed by Fisher exact test. Results: C belli was identified in 39/401 (9.7%) of the retrospective cohort, and 6/22 (27.3%) of the entirely submitted specimens. The presence of C belli showed no correlation with age, sex, clinical indication, or laboratory abnormalities. Conclusions: C belli resides in a latent state in the gallbladder and may be best considered a commensal organism.

Indexed as

AdolescentAdultCholecystectomyCoccidiaCoccidiosisCohort StudiesFemaleGallbladderGallbladder DiseasesHumansMaleMiddle AgedPrevalenceProspective StudiesRetrospective StudiesYoung Adult

Identifiers

PMID30285068
PMCPMC6287653

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.