Evidence map›Paper›PMID 30284958›Full record

ArticleTissue engineering. Part A2019

Production of Tissue-Engineered Small Intestine in Rats with Different Ages of Cell Donors.

Yanchun Liu, Yijie Wang, Jason Chakroff, Jed Johnson, Aidan Farrell, Gail E Besner

Open access · greenAbstract read
In one paragraph

Article in Tissue engineering. Part A, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yanchun Liu1 The Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
Yijie Wang1 The Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
Jason Chakroff2 Nanofiber Solutions, Hilliard, Ohio.
Jed Johnson2 Nanofiber Solutions, Hilliard, Ohio.
Aidan Farrell1 The Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
Gail E Besner1 The Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
Nationwide Children's Hospital · USNanofiber Solutions (United States) · US

Funding

Tissue Engineered IntestineR43DK107168 · NIDDK · NANOFIBER SOLUTIONS, LLC · PI JOHNSON, JED KIZER · 2015 to 2015
$250k
NIDDK NIH HHS R43 DK107168
6 · The paper itself

Abstract

impact statementThis study compared side-by-side the impact of donor age on the production of tissue-engineered small intestine (TESI). Each age represents a specific period of life: E18 for fetuses, 5-day-old pups for neonates, 21-day-old rats for weanlings, and 6-week-old rats for adults. The TESI produced was compared macroscopically and microscopically. The mechanism(s) contributing to the differences observed was explored by detecting proliferating cells in the TESI and by analyzing intestinal stem cell gene expression in donor cells. These data may provide valuable information for future application of TESI clinically.

Indexed as

Tissue EngineeringAgingAnimalsCell DifferentiationCell ProliferationFemaleIntestine, SmallMaleOrganoidsRatsRats, Inbred LewStem CellsTissue Scaffoldsdonor ageintestinal stem cellstissue-engineered small intestinetissue maturation

Identifiers

PMID30284958
PMCPMC6590728
OpenAlexW2894829673

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.