ArticleMagnetic resonance in medicine2019
Multicenter reproducibility of quantitative susceptibility mapping in a gadolinium phantom using MEDI+0 automatic zero referencing.
Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 38 citations in OpenAlex.
- Evaluation of Phantom Doping Materials in Quantitative Susceptibility Mapping.Magnetic resonance in medicine · 2026Article
- Does quantitative susceptibility mapping elucidate age-related alterations in deep gray matter iron deposition? A systematic review.Radiological physics and technology · 2026Review
- Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism.Annals of clinical and translational neurology · 2026Article
- Sensitivity of multi-parametric quantitative magnetic resonance imaging for multiple sclerosis pathology.PloS one · 2025Article
- Quantitative susceptibility mapping is more sensitive and specific than phase imaging in detecting chronic active multiple sclerosis lesion rims: pathological validation.Brain communications · 2025Article
- Validation of deep-learning accelerated quantitative susceptibility mapping for deep brain nuclei.Frontiers in neuroscience · 2025Article
- Impact of paramagnetic rim lesions on disability and race in multiple sclerosis: mediation analysis.Annals of clinical and translational neurology · 2024Observational
- Phase-sensitive deep reconstruction method for rapid multiparametric MR fingerprinting and quantitative susceptibility mapping in the brain.Magnetic resonance imaging · 2024Article
- Interscanner reproducibility of volumetric quantitative susceptibility mapping about cerebral subcortical gray nuclei at different MR vendors with the same magnetic strength.Brain and behavior · 2024Article
- Magnetic susceptibility in the deep gray matter may be modulated by apolipoprotein E4 and age with regional predilections: a quantitative susceptibility mapping study.Neuroradiology · 2022Article
- Three-dimensional simultaneous brain mapping of T1, T2,Magnetic resonance in medicine · 2022Article
- Dimethyl Fumarate Reduces Inflammation in Chronic Active Multiple Sclerosis Lesions.Neurology(R) neuroimmunology & neuroinflammation · 2022Observational
- QSM reconstruction challenge 2.0: A realistic in silico head phantom for MRI data simulation and evaluation of susceptibility mapping procedures.Magnetic resonance in medicine · 2021Article
- Quantitative magnetic resonance imaging towards clinical application in multiple sclerosis.Brain : a journal of neurology · 2021Review
- Comparison of Phase Estimation Methods for Quantitative Susceptibility Mapping Using a Rotating-Tube Phantom.Radiology research and practice · 2021Article
- Integrated quantitative susceptibility and RNMR in biomedicine · 2021Article
- [Reproducibility analysis of quantitative susceptibility mapping of cerebral subcortical nuclei in healthy adults].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020Article
- Phantom validation of quantitative susceptibility and dynamic contrast-enhanced permeability MR sequences across instruments and sites.Journal of magnetic resonance imaging : JMRI · 2020Article
- Quantitative Susceptibility Mapping: MRI at 7T versus 3T.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2020Article
- Clinical Integration of Automated Processing for Brain Quantitative Susceptibility Mapping: Multi-Site Reproducibility and Single-Site Robustness.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2019Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 4 countries.
Funding
Abstract
purposeTo determine the reproducibility of quantitative susceptibility mapping at multiple sites on clinical and preclinical scanners (1.5 T, 3 T, 7 T, and 9.4 T) from different vendors (Siemens, GE, Philips, and Bruker) for standardization of multicenter studies.
methodsSeven phantoms distributed from the core site, each containing 5 compartments with gadolinium solutions with fixed concentrations between 0.625 mM and 10 mM. Multi-echo gradient echo scans were performed at 1.5 T, 3 T, 7 T, and 9.4 T on 12 clinical and 3 preclinical scanners. DICOM images from the scans were processed into quantitative susceptibility maps using the Laplacian boundary value (LBV) and MEDI+0 automatic uniform reference algorithm. Region of interest (ROI) analyses were performed by a physicist to determine agreement between results from all sites. Measurement reproducibility was assessed using regression, Bland-Altman plots, and the intra-class correlation coefficient (ICC).
resultsQuantitative susceptibility mapping (QSM) from all scanners had similar, artifact-free visual appearance. Regression analysis showed a linear relationship between gadolinium concentrations and average QSM measurements for all phantoms (y = 350x - 0.0346, r
conclusionsQSM shows excellent multicenter reproducibility for a large range of susceptibility values encountered in cranial and extra-cranial applications on a diverse set of scanner platforms.
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