Trial reportSaudi medical journal2018
Effect of preoperative hydromorphone in patients undergoing laparoscopic radical gastrectomy. A double-blind, randomized and controlled trial.
Trial report in Saudi medical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 citations in OpenAlex.
- Molecular mechanism of hydromorphone preconditioning in cerebral ischemia/reperfusion‑induced inflammatory injury.International journal of molecular medicine · 2026Article
- Hydromorphone Protects against COOxidative medicine and cellular longevity · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo determine the efficacy of preemptive hydromorphone for laparoscopic radical gastrectomy. Methods: The present prospective and double-blinded study was performed in the The First Hospital, Jilin University, Changchun, China, between July 2017 and April 2018. Fifty patients scheduled for laparoscopic radical gastrectomy were equally randomized into 2 groups, which were administrated different drugs 10 minutes before surgery. Group P (the preemptive hydromorphone group) was administrated 2 mg hydromorphone (2 mL), and Group C (the control group) was administrated 2 mL normal saline intravenously. A standardized general anesthesia were conducted. Blood pressure and heart rate, postoperative morphine consumption, pain intensity, sedation status, and side effects were recorded. Results: Group C had larger intraoperative hemodynamic changes, higher postoperative visual analogue scale score, more morphine consumption and lower overall satisfaction degree than Group P. No difference was found between the 2 groups in sedation status and adverse effects. Conclusion: Preoperative 2 mg hydromorphone could reduce intraoperative changes of blood pressure and heart rate, postoperative pain intensity, and morphine consumption without an increase of adverse effects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.