Evidence map›Paper›PMID 30284370›Full record

ArticleJournal of applied clinical medical physics2018

Evaluation of offline adaptive planning techniques in image-guided brachytherapy of cervical cancer.

Han Liu, James Kinard, Jacqueline Maurer, Qingyang Shang, Caroline Vanderstraeten, Lane Hayes, Benjamin Sintay, David Wiant

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Han LiuDepartment of Radiation Oncology, Cone Health Cancer Center, Greensboro, NC, USA.
James KinardDepartment of Radiation Oncology, Cone Health Cancer Center, Greensboro, NC, USA.
Jacqueline MaurerDepartment of Radiation Oncology, Cone Health Cancer Center, Greensboro, NC, USA.
Qingyang ShangDepartment of Radiation Oncology, Cone Health Cancer Center, Greensboro, NC, USA.
Caroline VanderstraetenDepartment of Radiation Oncology, Cone Health Cancer Center, Greensboro, NC, USA.
Lane HayesDepartment of Radiation Oncology, Cone Health Cancer Center, Greensboro, NC, USA.
Benjamin SintayDepartment of Radiation Oncology, Cone Health Cancer Center, Greensboro, NC, USA.
David WiantDepartment of Radiation Oncology, Cone Health Cancer Center, Greensboro, NC, USA.
Cone Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern three-dimensional image-guided intracavitary high dose rate (HDR) brachytherapy is often used in combination with external beam radiotherapy (EBRT) to manage cervical cancer. Intrafraction motion of critical organs relative to the HDR applicator in the time between the planning CT and treatment delivery can cause marked deviations between the planned and delivered doses. This study examines offline adaptive planning techniques that may reduce intrafraction uncertainties by shortening the time between the planning CT and treatment delivery. Eight patients who received EBRT followed by HDR boosts were retrospectively reviewed. A CT scan was obtained for each insertion. Four strategies were simulated: (A) plans based on the current treatment day CT; (B) plans based on the first fraction CT; (C) plans based on the CT from the immediately preceding fraction; (D) plans based on the closest anatomically matched previous CT, using all prior plans as a library. Strategies B, C, and D allow plans to be created prior to the treatment day insertion, and then rapidly compared with the new CT. Equivalent doses in 2 Gy for combined EBRT and HDR were compared with online adaptive plans (strategy A) at D

Indexed as

BrachytherapyColon, SigmoidFemaleFollow-Up StudiesHumansImage Processing, Computer-AssistedOrgans at RiskPrognosisRadiotherapy DosageRadiotherapy, Image-GuidedRadiotherapy Planning, Computer-AssistedRectumRetrospective StudiesTomography, X-Ray ComputedUrinary BladderUterine Cervical NeoplasmsImage-guided brachytherapyoffline adaptive planning

Identifiers

PMID30284370
PMCPMC6236843
OpenAlexW2894769731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.