Evidence map›Paper›PMID 30284156›Full record

ArticleJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology2018

Reduction in Cannabis Use and Functional Status in Physical Health, Mental Health, and Cognition.

Larissa J Mooney, Yuhui Zhu, Caroline Yoo, Jonathan Valdez, Kevin Moino, Jung-Yu Liao, Yih-Ing Hser

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Evaluating cannabis use risk reduction as an alternative clinical outcome for cannabis use disorder.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Larissa J MooneyUCLA Department of Psychiatry and Biobehavioral Sciences, UCLA Integrated Substance Abuse Programs, University of California Los Angeles, 11075 Santa Monica Blvd., Suite 200, Los Angeles, CA, 90025, USA. lmooney@mednet.ucla.edu.ORCID 0000-0003-1556-731X
Yuhui ZhuUCLA Department of Psychiatry and Biobehavioral Sciences, UCLA Integrated Substance Abuse Programs, University of California Los Angeles, 11075 Santa Monica Blvd., Suite 200, Los Angeles, CA, 90025, USA.
Caroline YooUCLA Department of Psychiatry and Biobehavioral Sciences, UCLA Integrated Substance Abuse Programs, University of California Los Angeles, 11075 Santa Monica Blvd., Suite 200, Los Angeles, CA, 90025, USA.
Jonathan ValdezUCLA Department of Psychiatry and Biobehavioral Sciences, UCLA Integrated Substance Abuse Programs, University of California Los Angeles, 11075 Santa Monica Blvd., Suite 200, Los Angeles, CA, 90025, USA.
Kevin MoinoUCLA Department of Psychiatry and Biobehavioral Sciences, UCLA Integrated Substance Abuse Programs, University of California Los Angeles, 11075 Santa Monica Blvd., Suite 200, Los Angeles, CA, 90025, USA.
Jung-Yu LiaoDepartment of Health Promotion and Health Education, National Taiwan Normal University, 162, Section 1, Heping E. Rd, Taipei City, 106, Taiwan.
Yih-Ing HserUCLA Department of Psychiatry and Biobehavioral Sciences, UCLA Integrated Substance Abuse Programs, University of California Los Angeles, 11075 Santa Monica Blvd., Suite 200, Los Angeles, CA, 90025, USA.

Funding

Assessing Functional Outcomes Associated with Reductions in Cannabis UseR33DA042280 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HSER, YIH-ING, MOONEY, LARISSA JEANETTE · 2019 to 2021
$1.7M
Assessing Functional Outcomes Associated with Reductions in Cannabis UseR21DA042280 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HSER, YIH-ING, MOONEY, LARISSA JEANETTE · 2016 to 2017
$316k
NIDA NIH HHS R21 DA042280NIDA NIH HHS R33 DA042280
6 · The paper itself

Abstract

Treatment for substance use disorders has traditionally been abstinence-oriented, but evaluating the merits of low-level cannabis use as potential treatment endpoint may identify benefits that are clinically relevant for treatment-seeking individuals who do not attain abstinence. This study explores if reduction in cannabis use to a lower level of use is related to improved physical health, mental health, and perceived cognitive functions. Study participants with a history of problematic cannabis use (n = 111) completed assessments. Regression models were used to explore the relationship between past 30-day cannabis use levels (abstinent [57%], low use [22%] defined as less than or equal to 3 days per week, and heavy use [22%] defined as 4 or more days of use per week) and functional status in physical health, mental health, and cognition. Compared to heavy users, both abstinent and low-use individuals were similarly associated with better global health, appetite, and depression outcomes. Abstinent users also reported improved sleep, anxiety, and self-reported cognitive functioning relative to heavy users. Thus, reduction in cannabis use to lower levels is associated with beneficial outcomes important to health and other areas of functioning in individuals with problematic cannabis use.

Indexed as

Health StatusMental HealthAdultCognitionCross-Sectional StudiesFemaleHumansMaleMarijuana AbuseMarijuana SmokingMiddle AgedCannabis useCognitionFunctional outcomesHealthMental health

Identifiers

PMID30284156
PMCPMC6293461

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.