ArticleDigestive diseases and sciences2019
Delayed Bleeding After Colorectal Endoscopic Submucosal Dissection: When Is Emergency Colonoscopy Needed?
Article in Digestive diseases and sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Review on colorectal endoscopic submucosal dissection focusing on the technical aspect.Surgical endoscopy · 2020Pooled it
- Defect closure after endoscopic submucosal dissection decreased the adverse events in patients with large rectal neoplasms: a propensity score matching analysis.Surgical endoscopy · 2025Article
- Delphi consensus statement for the management of delayed post-polypectomy bleeding.Therapeutic advances in gastroenterology · 2025Article
- Establishing a nomogram for predicting the risk factors for delayed bleeding after endoscopic submucosal dissection for colorectal tumors.International journal of colorectal disease · 2024Article
- The Management of Direct Oral Anticoagulants for Colorectal Endoscopic Submucosal Dissection: A Multicenter Observational Study.Digestive diseases and sciences · 2024Observational
- Article
- Management of complications related to colorectal endoscopic submucosal dissection.Clinical endoscopy · 2023Review
- Complications after endoscopic submucosal dissection for early colorectal cancer (Review).Oncology letters · 2023Review
- [Research Progress in Delayed Bleeding after Endoscopic Submucosal Dissection of Early-Stage Gastrointestinal Cancer].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2022Review
- Propensity score matching analysis to evaluate efficacy of polyethylene oxide adhesive on preventing delayed bleeding after gastric endoscopic submucosal dissection.Scientific reports · 2022Article
- Clip-assisted endoloop ligation of the mucosal defect after resection of colorectal polyps decreased postprocedural delayed bleeding.Therapeutic advances in gastroenterology · 2022Article
- Risk factors for delayed bleeding after endoscopic submucosal dissection of colorectal tumors.Surgical endoscopy · 2021Article
- Efficacy and safety of colorectal endoscopic submucosal dissection in patients with sarcopenia.Surgical endoscopy · 2021Article
- Impact of obesity in colorectal endoscopic submucosal dissection: single-center retrospective cohort study.BMC gastroenterology · 2021Article
- Palisade technique as an effective endoscopic submucosal dissection tool for large colorectal tumors.Endoscopy international open · 2021Article
- The Efficacy and Safety of a Promising Single-Channel Endoscopic Closure Technique for Endoscopic Treatment-Related Artificial Ulcers: A Pilot Study.Gastrointestinal tumors · 2020Article
- Predictive Factors of Mild and Severe Fibrosis in Colorectal Endoscopic Submucosal Dissection.Digestive diseases and sciences · 2020Article
- Safety of Cold Snare Polypectomy in Patients Receiving Treatment with Antithrombotic Agents.Digestive diseases and sciences · 2019Article
- Management of Complications of Colorectal Submucosal Dissection.Clinical endoscopy · 2019Article
- Concise Commentary: Caution, Not Cauterization-Management of Post-ESD Colorectal Hemorrhage.Digestive diseases and sciences · 2019Article
Corrections and comments
- Commented on by
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndoscopic submucosal dissection (ESD) is an effective treatment for early-colorectal cancer. Although delayed bleeding is a serious potential complication, there is no consensus on the optimal protocol to determine which cases require emergency colonoscopy.
aimsThis study aimed to assess the risk factors for delayed bleeding after ESD and evaluate the "watch and wait" strategy for delayed bleeding. The "watch and wait" strategy was used for delayed bleeding, unless the shock index was ≥ 1 and/or a moderate amount of hematochezia occurred more than five occurrences.
methodsThis study included 404 patients who had undergone endoscopic resection for 439 lesions between April 2012 and February 2018. Patients were classified into the bleeding group or the no-bleeding group to investigate the risk factors for delayed bleeding, and to assess the necessity of emergency colonoscopy.
resultsTwenty-seven patients into the bleeding group and 412 into the no-bleeding group were classified. However, no case required emergency colonoscopy for hemostasis under "watch and wait strategy." Multivariate analysis revealed the risk factors for bleeding were rectal lesion (OR 5.547, 95% CI 1.456-21.130; P = 0.012) and lesion size ≥ 40 mm (OR 3.967, 95% CI 1.003-15.696; P = 0.05).
conclusionsRisk factors for delayed bleeding are rectal lesions and lesion size ≥ 40 mm. This watch and wait strategy resulted in no requirements for emergency colonoscopy or blood transfusion, and no serious conditions caused by delayed bleeding.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.