Evidence map›Paper›PMID 30284091›Full record

ArticleInternational ophthalmology2019

MP-3 measurement of retinal sensitivity in macular hole area and its predictive value on visual prognosis.

Zengyi Wang, Yue Qi, Xida Liang, Yanping Yu, Jinqiu Chen, Jing Wang, Xinxin Liu, Wu Liu

Registry-linked trialAbstract read
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In one paragraph

Article in International ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04135638 (Comparing Retinal Sensitivity and Fixation Stability of Inverted ILM-flap Techniques Variants for Macular Hole Surgery), which is not on this map. Cited by 13 papers.

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0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04135638 naunknown statusnot on this map

Comparing Retinal Sensitivity and Fixation Stability of Inverted ILM-flap Techniques Variants for Macular Hole Surgery

TypeinterventionalSponsorUniversity of MoliseRan2019 to 2020Enrolled28ConditionsMacular HolesArmsCover Group, Fill Group
3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zengyi WangBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, No.1 Dongjiaominxiang, Dongcheng District, Beijing, 100730, China.
Yue QiBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, No.1 Dongjiaominxiang, Dongcheng District, Beijing, 100730, China.
Xida LiangBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, No.1 Dongjiaominxiang, Dongcheng District, Beijing, 100730, China.
Yanping YuBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, No.1 Dongjiaominxiang, Dongcheng District, Beijing, 100730, China.
Jinqiu ChenBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, No.1 Dongjiaominxiang, Dongcheng District, Beijing, 100730, China.
Jing WangBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, No.1 Dongjiaominxiang, Dongcheng District, Beijing, 100730, China.
Xinxin LiuBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, No.1 Dongjiaominxiang, Dongcheng District, Beijing, 100730, China.
Wu LiuBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, No.1 Dongjiaominxiang, Dongcheng District, Beijing, 100730, China. wuliubj@sina.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo explore a measuring method for retinal sensitivity in macular hole area by Microperimeter-3 (MP-3) and evaluate its predictive value on visual prognosis.

methodsThis was a case series study including 44 eyes of 44 patients with idiopathic macular hole. Retinal sensitivity inside and 0.5 degree outside the macular hole margin was measured, and its mean value was defined as macular hole sensitivity (MHS). Best-corrected visual acuity (BCVA), minimum diameter of macular hole (MD), IS/OS defect diameter, retinal sensitivity in 8 degrees and 2 degrees were also recorded preoperatively and 4 months after operation.

resultsAll macular holes were closed after surgery. BCVA was significantly improved from 1.06 ± 0.39 at baseline to 0.31 ± 0.24 at 4 months postoperatively (P < 0.001). Meanwhile, MHS was also significantly improved from 12.02 ± 3.74 dB at baseline to 20.72 ± 4.00 dB at 4 months postoperatively (P < 0.001). MD, preoperative IS/OS defect diameter, preoperative BCVA, preoperative retinal sensitivity in 8 degrees and 2 degrees, and preoperative MHS were all correlated with postoperative BCVA at 4 months, but only preoperative MHS showed liner relationships to postoperative BCVA at 4 months by multivariate stepwise linear analysis.

conclusionsMacular hole sensitivity by MP-3 could reflect the change of central retinal function after successful macular hole surgery. Compared to preoperative retinal sensitivity in 8 degrees and 2 degrees, preoperative macular hole sensitivity is a better predictor for visual prognosis.

Indexed as

Visual AcuityAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPredictive Value of TestsPreoperative PeriodPrognosisRetinaRetinal PerforationsRetrospective StudiesSeverity of Illness IndexTomography, Optical CoherenceVisual Field TestsIdiopathic macular holeThe MP-3 microperimetryVisual prognosisVitrectomy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.