Evidence map›Paper›PMID 30283994›Full record

ArticleWorld journal of urology2019

Minimally invasive prostatic urethral lift (PUL) efficacious in TURP candidates: a multicenter German evaluation after 2 years.

Karl-Dietrich Sievert, Martin Schonthaler, Richard Berges, Patricia Toomey, Desiree Drager, Annika Herlemann, Florian Miller, Ulrich Wetterauer, Bjorn Volkmer, Christian Gratzke and 1 more

Registry-linked trialOpen access · hybridAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06037356 (Prostatic Urethral Lift Versus Transurethral Resection of Prostate in Benign Prostatic Hyperplasia Patients With Urinary Retention), which is not on this map. Cited by 31 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 5 pooled it
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06037356 narecruitingnot on this mapstarted 2025, after this paper: background citation

Prostatic Urethral Lift Versus Transurethral Resection of Prostate in Benign Prostatic Hyperplasia Patients With Urinary Retention

TypeinterventionalSponsorQueen Mary Hospital, Hong KongRan2025 to 2035Enrolled100ConditionsBPH With Urinary ObstructionArmsProstatic Urethral Lift, TURP
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 5 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Local anesthesia for UroLiftWorld journal of urology · 2025
    Pooled it
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  11. Article
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  18. Article
  19. Office-Based Procedures for BPH.Current urology reports · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Karl-Dietrich SievertDepartment of Urology, University Clinic of Tubingen, Tuebingen, Germany. KD_Sievert@hotmail.com.ORCID http://orcid.org/0000-0003-4814-214X
Martin SchonthalerDepartment of Urology, University Clinic of Freiburg, Freiburg, Germany.
Richard BergesDepartment of Urology, PAN Klinik Köln, Cologne, Germany.
Patricia ToomeyDepartment of Urology, University Clinic of Tubingen, Tuebingen, Germany.
Desiree DragerDepartment of Urology, University Clinic of Rostock, Rostock, Germany.
Annika HerlemannDepartment of Urology, University Clinic of Munich, Munich, Germany.
Florian MillerDepartment of Urology, University Clinic of Tubingen, Tuebingen, Germany.
Ulrich WetterauerDepartment of Urology, University Clinic of Freiburg, Freiburg, Germany.
Bjorn VolkmerDepartment of Urology, Klinikum Kassel, Kassel, Germany.
Christian GratzkeDepartment of Urology, University Clinic of Munich, Munich, Germany.
Bastian AmendDepartment of Urology, University Clinic of Tubingen, Tuebingen, Germany.
University of Tübingen · DEMünchen Klinik · DEUniversity Medical Center Freiburg · DEKlinikum Kassel · DEKlinikum Lippe · DEUniversity of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSuccessful outcomes have been reported for the treatment of lower urinary tract symptoms (LUTS) with the prostatic urethral lift (PUL) in a number of clinical investigations. Our aim was to investigate PUL outcomes in patients treated in a day-to-day clinical setting without the rigid exclusion criteria of clinical studies. MATERIALS AND

methodsWe investigated the outcome of the PUL procedure at five German departments during the initial period when PUL was approved for the clinic (10/2012-06/2014). All candidates for transurethral resection of the prostate (TURP) received PUL information and were given the choice of procedures. The only exclusion criterion was an obstructive median lobe. No patients were excluded because of high post-void residual volume (PVR), prostate size, retention history or LUTS oral therapy. Maximum urinary flow (Qmax), PVR, International Prostate Symptom Score (IPSS) and Quality of Life (QOL) were assessed at baseline, 1, 6, 12, and 24 months after surgery.

resultsOf 212 TURP candidates, 86 choose PUL. A mean of 3.8 (2-7) UroLift implants were implanted in patients of 38-85 years with a prostate size of 17-111 ml over 57 (42-90) min under general or local anesthesia. Thirty-eight (38.4%) patients had severe BPH obstruction and would have been denied PUL utilizing previously reported study criteria. Within 1 month 74 (86%) reported substantial symptom relief with significant improvements in Qmax, PVR, IPSS, and QOL (p < 0.001) that was maintained within the follow-up. Sexual function including ejaculation was unchanged or improved. No Clavien-Dindo Grad ≥ 2 was reported postoperatively. Eleven (12.8%) patients were retreated over 2 years. Twelve (86%) of 14 patients presenting with chronic urinary retention were catheter free at last follow-up.

conclusionPUL is a promising surgical technique that may alleviate LUTS, even in patients with severe obstruction.

Indexed as

Minimally Invasive Surgical ProceduresProsthesis ImplantationUrologic Surgical Procedures, MaleAdultAgedAged, 80 and overGermanyHumansLower Urinary Tract SymptomsMaleMiddle AgedProstatic HyperplasiaQuality of LifeSeverity of Illness IndexTransurethral Resection of ProstateUrethral ObstructionBenign prostatic hyperplasia (BPH)LUTSMinimally invasive surgical therapyProstatic urethral lift (PUL)Transurethral resection of prostate

Identifiers

PMID30283994
PMCPMC6620255
OpenAlexW2894627899

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.