ReviewCellular and molecular life sciences : CMLS2019
Dynamics and mechanisms of posterior axis elongation in the vertebrate embryo.
Review in Cellular and molecular life sciences : CMLS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- Changes in cellular composition shape the inductive properties of Hensen's Node.Nature communications · 2025Article
- Extracellular volume expansion drives vertebrate axis elongation.Current biology : CB · 2025Article
- Spinal cord elongation enables proportional regulation of the zebrafish posterior body.Development (Cambridge, England) · 2025Article
- Programming the elongation of mammalian cell aggregates with synthetic gene circuits.bioRxiv : the preprint server for biology · 2024Article
- Differential proliferation regulates multi-tissue morphogenesis during embryonic axial extension: integrating viscous modeling and experimental approaches.Development (Cambridge, England) · 2024Article
- Mechanics of Anteroposterior Axis Formation in Vertebrates.Annual review of cell and developmental biology · 2019Review
Corrections and comments
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Authors and funding
1 author.
Funding
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Abstract
During development, the vertebrate embryo undergoes significant morphological changes which lead to its future body form and functioning organs. One of these noticeable changes is the extension of the body shape along the antero-posterior (A-P) axis. This A-P extension, while taking place in multiple embryonic tissues of the vertebrate body, involves the same basic cellular behaviors: cell proliferation, cell migration (of new progenitors from a posterior stem zone), and cell rearrangements. However, the nature and the relative contribution of these different cellular behaviors to A-P extension appear to vary depending upon the tissue in which they take place and on the stage of embryonic development. By focusing on what is known in the neural and mesodermal tissues of the bird embryo, I review the influences of cellular behaviors in posterior tissue extension. In this context, I discuss how changes in distinct cell behaviors can be coordinated at the tissue level (and between tissues) to synergize, build, and elongate the posterior part of the embryonic body. This multi-tissue framework does not only concern axis elongation, as it could also be generalized to morphogenesis of any developing organs.
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Registered trials
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