Evidence map›Paper›PMID 30283885›Full record

ArticleJBMR plus2017

Insulin-Stimulated Bone Blood Flow and Bone Biomechanical Properties Are Compromised in Obese, Type 2 Diabetic OLETF Rats.

Rebecca K Dirkes, Laura C Ortinau, R Scott Rector, T Dylan Olver, Pamela S Hinton

Open access · goldAbstract read
In one paragraph

Article in JBMR plus, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rebecca K DirkesDepartment of Nutrition and Exercise Physiology University of Missouri-Columbia Columbia MO USA.
Laura C OrtinauDepartment of Nutrition and Exercise Physiology University of Missouri-Columbia Columbia MO USA.
R Scott RectorDepartment of Nutrition and Exercise Physiology University of Missouri-Columbia Columbia MO USA.
T Dylan OlverDepartment of Biomedical Sciences University of Missouri-Columbia Columbia MO USA.
Pamela S HintonDepartment of Nutrition and Exercise Physiology University of Missouri-Columbia Columbia MO USA.
University of Missouri · USHarry S. Truman Memorial Veterans' Hospital · US

Funding

Hepatic Mitochondria and Insulin Resistance in Fatty Liver and Type 2 DiabetesIK2BX001299 · VA · HARRY S. TRUMAN MEMORIAL VA HOSPITAL · PI RECTOR, RANDY SCOTT · 2011 to 2015
–
BLRD VA IK2 BX001299
6 · The paper itself

Abstract

Type 2 diabetes (T2D) increases skeletal fragility and fracture risk; however, the underlying mechanisms remain to be identified. Impaired bone vascular function, in particular insulin-stimulated vasodilation and blood flow is a potential, yet unexplored mechanism. The purpose of this study was to determine the effects of T2D on femoral biomechanical properties, trabecular microarchitecture, and insulin-stimulated bone vasodilation by comparison of hyperphagic Otsuka Long-Evans Tokushima Fatty (OLETF) rats with normoglycemic control OLETF rats. Four-week old, male OLETF rats were randomized to two groups: type 2 diabetes (O-T2D) or normoglycemic control (O-CON). O-T2D were allowed

Indexed as

ANALYSIS/QUANITIFICATION OF BONEANIMAL MODELSBIOMECHANICSBONE QCT/µCTDISEASES AND DISORDERS OF/RELATED TO BONEDXAGENETIC ANIMAL MODELORTHOPAEDICSOTHER

Identifiers

PMID30283885
PMCPMC6124191
OpenAlexW2613493127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.