Evidence map›Paper›PMID 30283776›Full record

ArticleFrontiers in bioengineering and biotechnology2018

Photocrosslinkable Gelatin Hydrogels Modulate the Production of the Major Pro-inflammatory Cytokine, TNF-α, by Human Mononuclear Cells.

Amy R Donaldson, Constantin Edi Tanase, Dennis Awuah, Pranav Vasanthi Bathrinarayanan, Laurence Hall, Mehdi Nikkhah, Ali Khademhosseini, Felicity Rose, Cameron Alexander, Amir M Ghaemmaghami

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Bilayer gelatin-methacryloyl scaffold for pulp inflammation suppression and dentin-like tissue regeneration.Journal of controlled release : official journal of the Controlled Release Society · 2026
    Article
  3. Article
  4. Innovative Hydrogel Design: Tailoring Immunomodulation for Optimal Chronic Wound Recovery.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Rational Design of Immunomodulatory Hydrogels for Chronic Wound Healing.Advanced materials (Deerfield Beach, Fla.) · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amy R DonaldsonImmunology and Tissue Modelling Group, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Constantin Edi TanaseImmunology and Tissue Modelling Group, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Dennis AwuahImmunology and Tissue Modelling Group, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Pranav Vasanthi BathrinarayananImmunology and Tissue Modelling Group, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Laurence HallImmunology and Tissue Modelling Group, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Mehdi NikkhahSchool of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, United States.
Ali KhademhosseiniCenter for Minimally Invasive Therapeutics (C-MIT), California NanoSystems Institute (CNSI), University of California, Los Angeles, Los Angeles, CA, United States.
Felicity RoseDivision of Regenerative Medicine and Cellular Therapies, School of Pharmacy, University of Nottingham, Nottingham, United Kingdom.
Cameron AlexanderDivision of Molecular Therapeutics and Formulation, School of Pharmacy, University of Nottingham, Nottingham, United Kingdom.
Amir M GhaemmaghamiImmunology and Tissue Modelling Group, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.

Funding

National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/K500318/1
6 · The paper itself

Abstract

Hydrogels are an attractive class of biomaterials in tissue engineering due to their inherently compatible properties for cell culture. Gelatin methacryloyl (GelMA) has shown significant promise in the fields of tissue engineering and drug delivery, as its physical properties can be precisely tuned depending on the specific application. There is a growing appreciation for the interaction between biomaterials and cells of the immune system with the increasing usage of biomaterials for

Indexed as

biomaterialsGelatin methacryloylimmunologytissue engineeringTNF-α

Identifiers

PMID30283776
PMCPMC6156527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.