ReviewJournal of pharmacopuncture2018
A Systematic Review on Prevention and Treatment of Nipple Pain and Fissure: Are They Curable?
Review in Journal of pharmacopuncture, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 89 citations in OpenAlex.
- Prevention and management of nipple wound: a systematic review.BMC pregnancy and childbirth · 2026Pooled it
- Low-level laser therapy for nipple trauma and pain during breastfeeding: systematic review and meta-analysis.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025Pooled it
- Effectiveness of the Application of Lanolin, Aloe Vera, and Peppermint on Nipple Pain and Nipple Trauma in Lactating Mothers: A Systematic Review and Meta-Analysis.Maternal and child health journal · 2024Pooled it
- The effectiveness of the laid-back position on lactation-related nipple problems and comfort: a meta-analysis.BMC pregnancy and childbirth · 2021Pooled it
- Efficacy of a Topical Lanolin-Beeswax-Olive Oil Blend (RepoGen Cream) in Preventing Nipple Fissures in Breastfeeding Women: A Randomized Controlled Trial.Journal of cosmetic dermatology · 2025Trial
- Effectiveness of biological nurturing on early breastfeeding problems: a randomized controlled trial.International breastfeeding journal · 2020Trial
- Perceptions of Coping With Breastfeeding Pain: A Secondary Analysis.Journal of midwifery & women's healthTrial
- Ecological Beeswax Breast Pads Promote Breastfeeding in First-Time Mothers from the Valencian Community (Spain): A Randomized Trial.Healthcare (Basel, Switzerland) · 2025Article
- Effectiveness of moisturising therapy in treating nipple trauma: a systematic review protocol.BMJ open · 2024Article
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- Prebiotic Activity of Vaginal Lactobacilli on Bifidobacteria: from Concept to Formulation.Microbiology spectrum · 2023Article
- Effects of prenatal professional breastfeeding education for the family.Scientific reports · 2022Article
- The Effectiveness of Aloe Vera on Relief of Irritation and Nipple Pain in Lactating Women: Systematic Review and Meta-Analysis.Obstetrics and gynecology international · 2022Review
- Common breastfeeding problems experienced by lactating mothers during the first six months in Kinshasa.PloS one · 2022Article
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- Exploring women's perceptions of pain when breastfeeding using online forums.International breastfeeding journal · 2021Article
- Re-thinking lactation-related nipple pain and damage.Women's health (London, England)Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Averagely 80% to 90% of breastfeeding women experience the nipple pain and fissures. The important factor for successful breastfeeding is to treat this problem. This study has done as a review with the aim of analysis of the clinical trials in the field of the prevention and treatment of the nipple fissures and pain due to the importance of breastfeeding. For this purpose, the key words of sore, nipples, fissure, trauma, wound, prevention, treatment, therapeutics, therapy, clinical trial, breastfeeding and their Persian synonyms and all of their possible combinations were searched in the national databases: SID and Iran Medex and Magiran, and in the international databases: PubMed, Scopus, Medline, Science direct by May 2017. The Jadad criterion was used to assess the quality of the articles and the articles with a score of 3 or more were included in this study. Finally, 48 clinical trials were reviewed that 17 of them (sample size 1801) scored 3 or more based on the Jadad criterion. Seven articles were also in the non- drug treatment group (sample size 491) and 2 articles in the drug treatment group (sample size 337) and 8 articles in the herbal treatment group (sample size 973).The results show that menthol and warm water compress as well as teaching the correct breastfeeding methods are effective treatments to prevent and treat the nipple pain and fissures. Moreover, applying the herbal medicine for prevention and treatment of the issues raised from breastfeeding may have beneficial such as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.