ArticleWorld journal of gastrointestinal surgery2018
Systematic review of cystic duct closure techniques in relation to prevention of bile duct leakage after laparoscopic cholecystectomy.
Article in World journal of gastrointestinal surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05555810 (Suture Ligation Versus Clipping of Cystic Duct and Artery During Laparoscopic Cholecystectomy . " A Prospective Comparative Study"), which is not on this map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Suture Ligation Versus Clipping of Cystic Duct and Artery During Laparoscopic Cholecystectomy . " A Prospective Comparative Study"
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- How should we secure the cystic duct during laparoscopic cholecystectomy? A UK-wide survey of clinical practice and systematic review of the literature with meta-analysis.Annals of the Royal College of Surgeons of England · 2022Pooled it
- Postcholecystectomy diarrhoea rate and predictive factors: a systematic review of the literature.BMJ open · 2022Pooled it
- Pooled it
- Review
- Cystic Duct Diameter as a Key Predictor for Closure Difficulties in Laparoscopic Cholecystectomy.Cureus · 2025Article
- Impact of metal vs non-absorbable, polymer clips during laparoscopic cholecystectomy.Surgical endoscopy · 2025Article
- High rate of stone-related complications after stapling the cystic duct during laparoscopic cholecystectomy-an underrecognized risk.Surgical endoscopy · 2023Article
- Evaluation of 30-day morbidity and mortality of laparoscopic cholecystectomy: a multicenter prospective observational Indian Association of Gastrointestinal Endoscopic Surgeons (IAGES) Study.Surgical endoscopy · 2023Observational
- Noninvasive detection of pancreatic ductal adenocarcinoma using the methylation signature of circulating tumour DNA.BMC medicine · 2022Article
- Evidence-based surgery for laparoscopic cholecystectomy.Surgery open science · 2022Article
- Risk identification and technical modifications reduce the incidence of post-cholecystectomy bile leakage: analysis of 5675 laparoscopic cholecystectomies.Langenbeck's archives of surgery · 2022Article
- Evaluation of the safety of using harmonic scalpel during laparoscopic cholecystectomy in children: A preliminary report.Frontiers in pediatrics · 2022Article
- ClipAssistNet: bringing real-time safety feedback to operating rooms.International journal of computer assisted radiology and surgery · 2022Article
- Selective Trans-Catheter Coil Embolization of Cystic Duct Stump in Post-Cholecystectomy Bile Leak.Digestive diseases and sciences · 2019Article
- Safe laparoscopic cholecystectomy: Adoption of universal culture of safety in cholecystectomy.World journal of gastrointestinal surgery · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo study the effect of different techniques of cystic duct closure on bile leakage after laparoscopic cholecystectomy (LC) for biliary disease.
methodsA systematic search of MEDLINE, Cochrane and EMBASE was performed. Rate of cystic duct leakage (CDL) was the primary outcome. Risk of bias was evaluated. Odds ratios were analyzed for comparison of techniques and pooled event rates for non-comparative analyses. Pooled event rates were compared for each of included techniques.
resultsOut of 1491 articles, 38 studies were included. A total of 47491 patients were included, of which 38683 (81.5%) underwent cystic duct closure with non-locking (metal) clips. All studies were of low-moderate methodological quality. Only two studies reported separate data on uncomplicated and complicated gallbladder disease. For overall CDL, an odds ratio of 0.4 (95%CI: 0.06-2.48) was found for harmonic energy
conclusionBased on available evidence it is not possible to either recommend or discourage any of the techniques for cystic duct closure during LC with respects to CDL, although data point out a slight preference for locking clips and ligatures
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.