Evidence map›Paper›PMID 30283599›Full record

ReviewWorld journal of gastrointestinal endoscopy2018

Endoscopic therapy for Barrett's esophagus and early esophageal cancer: Where do we go from here?

Tavankit Singh, Madhusudhan R Sanaka, Prashanthi N Thota

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastrointestinal endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. How are we measuring health-related quality of life in patients with a Barrett Esophagus? A systematic review on patient-reported outcome measurements.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Endoscopic therapies for Barrett's esophagus.Translational gastroenterology and hepatology · 2021
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Current surgical treatment of esophagogastric junction adenocarcinoma.World journal of gastrointestinal oncology · 2019
    Review
  11. The role of ablation in the treatment of dysplastic Barrett's esophagus.Therapeutic advances in gastrointestinal endoscopy
    Review
  12. The evolution of endoscopic therapy for Barrett's esophagus.Therapeutic advances in gastrointestinal endoscopy
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tavankit SinghDepartment of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, OH 44195, United States.
Madhusudhan R SanakaDepartment of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, OH 44195, United States.
Prashanthi N ThotaDepartment of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, OH 44195, United States. thotap@ccf.org.
Cleveland Clinic · US

Funding

Whole Exome Approaches for Esophageal Adenocarcinoma Susceptibility GenesU54CA163060 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI CHAK, AMITABH, GUDA, KISHORE · 2011 to 2022
$14.0M
NCI NIH HHS U54 CA163060
6 · The paper itself

Abstract

Since Barrett's esophagus is a precancerous condition, efforts have been made for its eradication by various ablative techniques. Initially, laser ablation was attempted in non-dysplastic Barrett's esophagus and subsequently, endoscopic ablation using photodynamic therapy was used in Barrett's patients with high-grade dysplasia who were poor surgical candidates. Since then, various ablative therapies have been developed with radiofrequency ablation having the best quality of evidence. Resection of dysplastic areas only without complete removal of entire Barrett's segment is associated with high risk of developing metachronous neoplasia. Hence, the current standard of management for Barrett's esophagus includes endoscopic mucosal resection of visible abnormalities followed by ablation to eradicate remaining Barrett's epithelium. Although endoscopic therapy cannot address regional lymph node metastases, such nodal involvement is present in only 1% to 2% of patients with intramucosal adenocarcinoma in Barrett esophagus and therefore is useful in intramucosal cancers. Post ablation surveillance is recommended as recurrence of intestinal metaplasia and dysplasia have been reported. This review includes a discussion of the technique, efficacy and complication rate of currently available ablation techniques such as radiofrequency ablation, cryotherapy, argon plasma coagulation and photodynamic therapy as well as endoscopic mucosal resection. A brief discussion of the emerging technique, endoscopic submucosal dissection is also included.

Indexed as

AdenocarcinomaBarrett’s esophagusDysplasiaEndoscopic mucosal resectionEndoscopic therapyRadiofrequency ablation

Identifiers

PMID30283599
PMCPMC6162248
OpenAlexW2891701670

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.