Evidence map›Paper›PMID 30283456›Full record

ArticleFrontiers in immunology2018

Active Tuberculosis Is Characterized by Highly Differentiated Effector Memory Th1 Cells.

Riccardo Arrigucci, Karim Lakehal, Pooja Vir, Deborah Handler, Amy L Davidow, Rosa Herrera, Julia Dolores Estrada-Guzmán, Yuri Bushkin, Sanjay Tyagi, Alfred A Lardizabal and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Riccardo ArrigucciPublic Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Karim LakehalPublic Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Pooja VirPublic Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Deborah HandlerGlobal Tuberculosis Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Amy L DavidowDepartment of Biostatistics, School of Public Health, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Rosa HerreraFacultad de Medicina Mexicali, Universidad Autónoma de Baja California, Mexicali, Mexico.
Julia Dolores Estrada-GuzmánFacultad de Medicina Mexicali, Universidad Autónoma de Baja California, Mexicali, Mexico.
Yuri BushkinPublic Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Sanjay TyagiPublic Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Alfred A LardizabalGlobal Tuberculosis Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Maria Laura GennaroPublic Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Rutgers, The State University of New Jersey · USUniversidad Autónoma de Baja California · MXBiostat (United States) · US

Funding

FISH-Flow platform for host-based tuberculosis diagnosticsR01AI104615 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI GENNARO, MARIA LAURA · 2013 to 2017
$5.5M
Rapid Analysis of Single T Cell Immunity Signatures in TuberculosisR01AI106036 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI BUSHKIN, YURI, GENNARO, MARIA LAURA · 2012 to 2016
$3.8M
NIAID NIH HHS R01 AI104615NIAID NIH HHS R01 AI106036
6 · The paper itself

Abstract

Despite advances in diagnosing latent

Indexed as

AdultAgedCD4-Positive T-LymphocytesCell DifferentiationCells, CulturedFemaleHumansImmunologic MemoryImmunologic TestsInterferon-gammaLatent TuberculosisMaleMiddle AgedMycobacterium tuberculosisTh1 CellsTuberculosisInterferon-gammaTumor Necrosis Factor-alphacytokineFISH-Flowflow cytometryimmunophenotypingmemory T cellssingle-cell gene expressionT cell activation

Identifiers

PMID30283456
PMCPMC6156157
OpenAlexW2891664089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.