Evidence map›Paper›PMID 30283449›Full record

ArticleFrontiers in immunology2018

Glibenclamide Reduces Primary Human Monocyte Functions Against Tuberculosis Infection by Enhancing M2 Polarization.

Chidchamai Kewcharoenwong, Satria A Prabowo, Gregory J Bancroft, Helen A Fletcher, Ganjana Lertmemongkolchai

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Frontiers in pharmacology · 2022
    Article
  12. Article
  13. Decreased classical monocytes and CD163 expression in TB patients: an indicator of drug resistance.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Article
  14. Article
  15. Changes in Host Response toFrontiers in cellular and infection microbiology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Chidchamai KewcharoenwongMekong Health Science Research Institute, Khon Kaen, Thailand.
Satria A PrabowoDepartment of Immunology and Infection, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Gregory J BancroftDepartment of Immunology and Infection, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Helen A FletcherDepartment of Immunology and Infection, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Ganjana LertmemongkolchaiMekong Health Science Research Institute, Khon Kaen, Thailand.
London School of Hygiene & Tropical Medicine · GBKhon Kaen University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) is a global public health problem, which is caused by

Indexed as

AdultAgedCells, CulturedDiabetes Mellitus, Type 2FemaleGlyburideHumansHypoglycemic AgentsLectins, C-TypeMacrophage ActivationMacrophagesMaleMannose-Binding LectinsMannose ReceptorMiddle AgedMonocytesGlyburideHypoglycemic AgentsLectins, C-TypeMannose-Binding LectinsMannose ReceptorReceptors, Cell Surfaceanti-diabetic drugdiabetes mellitusglibenclamideM2 polarizationmonocyteMycobacterium tuberculosis

Identifiers

PMID30283449
PMCPMC6157405
OpenAlexW2891810803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.