Evidence map›Paper›PMID 30283354›Full record

ArticleFrontiers in physiology2018

Partial Mechanical Unloading of the Heart Disrupts L-Type Calcium Channel and Beta-Adrenoceptor Signaling Microdomains.

Peter T Wright, Jose L Sanchez-Alonso, Carla Lucarelli, Anita Alvarez-Laviada, Claire E Poulet, Sean O Bello, Giuseppe Faggian, Cesare M Terracciano, Julia Gorelik

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Scanning Ion Conductance Microscopy.Chemical reviews · 2021
    Review
  5. Review
  6. Article
  7. Review
  8. Studying signal compartmentation in adult cardiomyocytes.Biochemical Society transactions · 2020
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Peter T WrightMyocardial Function, National Heart and Lung Institute, Imperial College London, Imperial Centre for Translational and Experimental Medicine, Hammersmith Hospital, London, United Kingdom.
Jose L Sanchez-AlonsoMyocardial Function, National Heart and Lung Institute, Imperial College London, Imperial Centre for Translational and Experimental Medicine, Hammersmith Hospital, London, United Kingdom.
Carla LucarelliMyocardial Function, National Heart and Lung Institute, Imperial College London, Imperial Centre for Translational and Experimental Medicine, Hammersmith Hospital, London, United Kingdom.
Anita Alvarez-LaviadaMyocardial Function, National Heart and Lung Institute, Imperial College London, Imperial Centre for Translational and Experimental Medicine, Hammersmith Hospital, London, United Kingdom.
Claire E PouletMyocardial Function, National Heart and Lung Institute, Imperial College London, Imperial Centre for Translational and Experimental Medicine, Hammersmith Hospital, London, United Kingdom.
Sean O BelloMyocardial Function, National Heart and Lung Institute, Imperial College London, Imperial Centre for Translational and Experimental Medicine, Hammersmith Hospital, London, United Kingdom.
Giuseppe FaggianDepartment of Cardiac Surgery, School of Medicine, University of Verona, Verona, Italy.
Cesare M TerraccianoMyocardial Function, National Heart and Lung Institute, Imperial College London, Imperial Centre for Translational and Experimental Medicine, Hammersmith Hospital, London, United Kingdom.
Julia GorelikMyocardial Function, National Heart and Lung Institute, Imperial College London, Imperial Centre for Translational and Experimental Medicine, Hammersmith Hospital, London, United Kingdom.
Hammersmith Hospital · GBImperial College London · GBUniversity of Verona · IT

Funding

British Heart Foundation NH/10/3/28574British Heart Foundation PG/14/23/30723British Heart Foundation PG/17/3/32722Medical Research Council MR/L006855/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

beta-adrenergiccalciumcAMPcardiacexcitation-contractionmicrodomainst-tubulesunloading

Identifiers

PMID30283354
PMCPMC6157487
OpenAlexW2891282201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.