Evidence map›Paper›PMID 30283316›Full record

ArticleCase reports in oncology

Extracranial Metastases of a Cerebral Glioblastoma: A Case Report and Review of the Literature.

Jurij Rosen, Tobias Blau, Stefan J Grau, Michael T Barbe, Gereon R Fink, Norbert Galldiks

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 68 citations in OpenAlex.

  1. Article
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  4. Glioblastoma with an uncommonContemporary oncology (Poznan, Poland) · 2026
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  12. Extracranial metastasis of glioblastoma: A case report and literature review.International journal of surgery case reports · 2023
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  13. Review
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  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jurij RosenDepartment of Neurology, University of Cologne, Cologne, Germany.
Tobias BlauInstitute of Neuropathology, University of Cologne, Cologne, Germany.
Stefan J GrauDepartment of Neurosurgery, University of Cologne, Cologne, Germany.
Michael T BarbeDepartment of Neurology, University of Cologne, Cologne, Germany.
Gereon R FinkDepartment of Neurology, University of Cologne, Cologne, Germany.
Norbert GalldiksDepartment of Neurology, University of Cologne, Cologne, Germany.
University of Cologne · DEForschungszentrum Jülich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The glioblastoma, a malignant human brain tumor, is known for its devastating intracranial progress and its dismal prognosis. Whereas treatment and research are most prominently focused on the primary tumor lesion, in recent years evidence has accumulated that points to the rare occurrence of extracranial glioblastoma metastases. We here present a case of a female patient with a known glioblastoma who was detected to harbor multiple metastases in the bones, lung, pleura, liver, mesentery, and the subcutaneous soft tissue. Pathogenetically, these metastatic lesions developed most probably after a local progression of the left temporal glioblastoma through the skull base, thus getting access to the systemic lymphatics. Similar cases of extensive glioblastoma metastization, their putative underlying mechanisms, and implications for clinical care are discussed.

Indexed as

ChemotherapyExtraneural metastasisGliomaRadiotherapyTumor resection

Identifiers

PMID30283316
PMCPMC6167720
OpenAlexW2889284759

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.