Evidence map›Paper›PMID 30283010›Full record

ArticleScientific reports2018

Bufonid herpesvirus 1 (BfHV1) associated dermatitis and mortality in free ranging common toads (Bufo bufo) in Switzerland.

Francesco C Origgi, Benedikt R Schmidt, Petra Lohmann, Patricia Otten, Roman K Meier, Simone R R Pisano, Gaia Moore-Jones, Marco Tecilla, Ursula Sattler, Thomas Wahli and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. First Isolation of a Herpesvirus (FamilyAnimals : an open access journal from MDPI · 2022
    Article
  8. Article
  9. Article
  10. Consensus PCR protocols for the detection of amphibian herpesviruses (Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Francesco C OriggiCentre for Fish and Wildlife Health (FIWI), Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Länggassstrasse 122, 3001, Bern, Switzerland. francesco.origgi@vetsuisse.unibe.ch.
Benedikt R SchmidtInfo fauna Karch, UniMail, Batiment G, Bellevaux 51, 2000, Neuchâtel, Switzerland.ORCID http://orcid.org/0000-0002-4023-1001
Petra LohmannVeterinarian, 8127, Forch, Switzerland.
Patricia OttenFasteris SA, Geneva, Switzerland.
Roman K MeierCentre for Fish and Wildlife Health (FIWI), Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Länggassstrasse 122, 3001, Bern, Switzerland.
Simone R R PisanoCentre for Fish and Wildlife Health (FIWI), Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Länggassstrasse 122, 3001, Bern, Switzerland.
Gaia Moore-JonesCentre for Fish and Wildlife Health (FIWI), Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Länggassstrasse 122, 3001, Bern, Switzerland.
Marco TecillaUniversity of Milan, Milan, Italy.
Ursula SattlerCentre for Fish and Wildlife Health (FIWI), Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Länggassstrasse 122, 3001, Bern, Switzerland.
Thomas WahliCentre for Fish and Wildlife Health (FIWI), Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Länggassstrasse 122, 3001, Bern, Switzerland.
Veronique GaschenDivision of Veterinary Anatomy, University of Bern, POB, Bern, Switzerland.
Michael H StoffelDivision of Veterinary Anatomy, University of Bern, POB, Bern, Switzerland.
University of Bern · CHFederal Food Safety and Veterinary Office · CHUniversity of Milan · ITUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we report the discovery and partial characterization of a novel herpesvirus tentatively named Bufonid herpesvirus 1 (BfHV1) from severe dermatitis in free ranging common toads (Bufo bufo) in Switzerland. The disease has been observed in toads every year since 2014, in spring, during the mating season, at different and distant locations. The virus is found in the skin and occasionally in the brain of infected toads. The genome of the virus is at least 158 Kb long and contains at least 152 open reading frames with a minimal length of 270 nt. The genome of BfHV1 contains all the signature genes that are present in alloherpesviruses. Phylogenetic analysis based on the amino acid sequence of the DNA polymerase and terminase proteins positions the novel virus among the members of the genus Batrachovirus, family Alloherpesviridae. This is the first herpesvirus ever characterized in common toads.

Indexed as

Amino Acid SequenceAnimalsBufo bufoDermatitisDNA VirusesGenome, ViralHerpesviridaeHerpesvirus 1, HumanHumansPhylogenySwitzerland

Identifiers

PMID30283010
PMCPMC6170376
OpenAlexW2893395771

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.