Evidence map›Paper›PMID 30282997›Full record

ArticleScientific reports2018

Inhibition of the gyrA promoter by transcription-coupled DNA supercoiling in Escherichia coli.

Samantha Dages, Kelley Dages, Xiaoduo Zhi, Fenfei Leng

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. In Vivo Genomic Supercoiling Mapping Using Psora-seq.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. MoCloFlex: A Modular Yet Flexible Cloning System.Frontiers in bioengineering and biotechnology · 2019
    Article
  14. DNA Supercoiling: an Ancestral Regulator of Gene Expression in Pathogenic Bacteria?Computational and structural biotechnology journal · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Samantha DagesBiomolecular Sciences Institute, Florida International University, 11200 SW 8th Street, Miami, FL, 33199, USA.
Kelley DagesBiomolecular Sciences Institute, Florida International University, 11200 SW 8th Street, Miami, FL, 33199, USA.
Xiaoduo ZhiBiomolecular Sciences Institute, Florida International University, 11200 SW 8th Street, Miami, FL, 33199, USA.
Fenfei LengBiomolecular Sciences Institute, Florida International University, 11200 SW 8th Street, Miami, FL, 33199, USA. lengf@fiu.edu.ORCID http://orcid.org/0000-0002-9024-1216
Florida International University · US

Funding

Targeting transcription-coupled DNA supercoiling for discovering antibiotics against bacterial DNA gyraseR21AI125973 · NIAID · FLORIDA INTERNATIONAL UNIVERSITY · PI LENG, FENFEI · 2017 to 2018
$478k
Transcription-Coupled DNA SupercoilingR15GM109254 · NIGMS · FLORIDA INTERNATIONAL UNIVERSITY · PI LENG, FENFEI · 2014 to 2014
$317k
NIAID NIH HHS R21 AI125973NIGMS NIH HHS R15 GM109254
6 · The paper itself

Abstract

The E. coli gyrA promoter (P

Indexed as

Gene Expression Regulation, BacterialPromoter Regions, GeneticTranscription, GeneticAnti-Bacterial AgentsBase Sequencebeta-GalactosidaseChromosomes, BacterialCiprofloxacinDNA, BacterialDNA GyraseDNA, SuperhelicalEscherichia coliGenes, ReporterIsopropyl ThiogalactosideLuciferasesModels, GeneticAnti-Bacterial Agentsbeta-GalactosidaseCiprofloxacinDNA, BacterialDNA GyraseDNA, SuperhelicalIsopropyl ThiogalactosideLuciferasesNovobiocin

Identifiers

PMID30282997
PMCPMC6170449
OpenAlexW2894337529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.